SAB5702823

Anti-α-Actin-1 (ACTA1) antibody

rabbit monoclonal, 8T8D0

• Synonyme(s) : ACTA, ASMA, CFTD, CFTD1, CFTDM, MPFD, NEM1, NEM2, NEM3, SHPM
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.46

Propriétés

• Nom du produit: Anti-α-Actin-1 (ACTA1) Antibody, clone 8T8D0, Rabbit Monoclonal,
• Source biologique: rabbit
• Niveau de qualité: 100
• Matériaux: colorless
• Clone: 8T8D0, monoclonal
• Forme: liquid
• Poids mol.: 42 kDa
• Espèces réactives: rat, human, rat
• Concentration: 0.8 mg/mL
• Technique(s): immunofluorescence: 1:50 - 1:200; western blot: 1:500 - 1:2000
• Couleur: colorless
• Isotype: IgG
• Séquence immunogène: MCDEDETTALVCDNGSGLVKAGFAGDDAPRAVFPSIVGRPRHQGVMVGMGQKDSYVGDEAQSKRGILTLKYPIEHGIITNWDDMEKIWHHTFYNELRVAP
• Numéro d'accès UniProt: P68133
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... Actin(58)

Description

Description générale

The product encoded by this gene belongs to the actin family of proteins, which are highly conserved proteins that play a role in cell motility, structure and integrity. Alpha, beta and gamma actin isoforms have been identified, with alpha actins being a major constituent of the contractile apparatus, while beta and gamma actins are involved in the regulation of cell motility. This actin is an alpha actin that is found in skeletal muscle. Mutations in this gene cause nemaline myopathy type 3, congenital myopathy with excess of thin myofilaments, congenital myopathy with cores, and congenital myopathy with fiber-type disproportion, diseases that lead to muscle fiber defects. [provided by RefSeq, Jul 2008]

Immunogène

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human α-Actin-1 (ACTA1) (P68133).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1