SAB5600078

Anti-Integrin alpha 4 antibody, Rabbit monoclonal

recombinant, expressed in HEK 293 cells, clone RM268, purified immunoglobulin

• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Produit recombinant: expressed in HEK 293 cells
• Niveau de qualité: 100
• Forme d'anticorps: purified immunoglobulin
• Type de produit anticorps: primary antibodies
• Clone: RM268, monoclonal; recombinant monoclonal
• Forme: buffered aqueous glycerol solution
• Espèces réactives: human
• Technique(s): immunoblotting: 1:1000-1:2000; immunohistochemistry: 1:1000-1:5000
• Isotype: IgG
• Numéro d'accès NCBI: 3676
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ITGA4(3676)

Description

Description générale

Integrin subunit α4 (ITGA4) is an adhesive factor, that is part of the integrin family. The gene encoding it is localized on human chromosome 2q31.3.

Spécificité

This antibody reacts to the cytoplasmic domain of human Integrin alpha 4 (ITGA4).

Immunogène

Synthetic peptide corresponding to the C-terminus of human Integrin alpha 4 (ITGA4)

Actions biochimiques/physiologiques

Integrin subunit α 4 (ITGA4) has a role in bone marrow homing. It associates with the β1 integrin chain and forms the very-late-antigen-4 (VLA-4) complex. The protein also binds to vascular cell adhesion molecule-1, fibronectin and osteopontin (OPN) and modulates the activity of immature progenitors in the bone marrow. ITGA4 also aids the migration of B lymphocytes through the fibroblast barrier.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Forme physique

Solution in phosphate buffered saline containing 50% glycerol, 1% BSA and 0.09% sodium azide.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 2
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable