SAB4702018

Monoclonal Anti-CRP purified produced in mouse

• Code UNSPSC : 12352203

Propriétés

• Conjugué: unconjugated
• Niveau de qualité: 100
• Type de produit anticorps: primary antibodies
• Clone: C2, monoclonal
• Forme: buffered aqueous solution
• Espèces réactives: human
• Concentration: 1 mg/ml
• Technique(s): ELISA: suitable; immunohistochemistry: suitable
• Isotype: IgG1
• Numéro d'accès UniProt: P02741
• Température de stockage: 2-8°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... CRP(1401)

Description

Description générale

The C-reactive protein (CRP) is a cyclic pentameric pentraxin family acute phase protein composed of five identical noncovalently bound nonglycosylated subunits (each subunit 24 kDa; physiologic CRP molecule 117,5 kDa). CRP is produced by the liver and its plasma levels rise dramatically during inflammatory processes occuring in the body. CRP is an initiator of classical complement cascade, binds to several nuclear components (chromatin, histones, etc.) and is also believed to play an important role in innate immunity. Patients with elevated basal levels of CRP are at increased risk for hypertension and cardiovascular disease.

Spécificité

The mouse monoclonal antibody C2 recognizes human CRP, an 117 kDa plasma acute phase protein; it recognizes the antigen both in the presence and in the absence (samples containing EDTA) of Ca2+.

Immunogène

Purified human CRP

Forme physique

Phosphate buffered saline (PBS), pH 7.4, 15 mM sodium azide

Notes préparatoires

Purified by protein-A affinity chromatography.

Stockage et stabilité

Store at 2-8°C. Do not freeze.

Autres remarques

The antibody solution should be gently mixed before use.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable