SAB4300592

Anti-PXN (Ab-88) antibody produced in rabbit

affinity isolated antibody

• Synonyme(s) : Anti-FLJ16691 antibody produced in rabbit, Anti-paxillin antibody produced in rabbit
• Code UNSPSC : 12352203
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Conjugué: unconjugated
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Forme: buffered aqueous solution
• Poids mol.: ~68 kDa
• Espèces réactives: human
• Concentration: 1 mg/mL
• Technique(s): indirect immunofluorescence: 1:50-1:100; western blot: 1:500-1:1000
• Isotype: IgG
• Séquence immunogène: (P-V-Y-G-S)
• Numéro d'accès NCBI: NP_001074324.1
• Numéro d'accès UniProt: P49023
• Conditions d'expédition: wet ice
• Température de stockage: −20°C
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... PXN(5829)

Description

Description générale

PXN (paxillin) is a focal adhesion-associated tyrosine-based protein, that is present in the cytoplasm. It is a 68kDa protein that is located on chromosome 12q24.

Immunogène

Peptide sequence around aa. 86-90 (P-V-Y-G-S), according to the protein PXN.

Application

Anti-PXN (Ab-88) antibody has been used in immunofluorescence.

Actions biochimiques/physiologiques

Paxillin (PXN) controls signal transduction, cell morphology and motility, cytoskeletal rearrangements, proliferation and apoptosis. It serves as an oncogene, hence it plays a major role in the growth of human carcinomas.

Caractéristiques et avantages

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Description de la cible

Cytoskeletal protein involved in actin-membrane attachment at sites of cell adhesion to the extracellular matrix (focal adhesion).

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 10 - Combustible liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable