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Principaux documents

SAB4300163

Sigma-Aldrich

Anti-phospho-RAC1 (pSer71) antibody produced in rabbit

affinity isolated antibody

Synonyme(s) :

Anti-MGC111543 antibody produced in rabbit, Anti-MIG5 antibody produced in rabbit, Anti-TC-25 antibody produced in rabbit, Anti-p21-Rac1 antibody produced in rabbit, Anti-ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody produced in rabbit

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About This Item

Numéro MDL:
MFCD01322704
Code UNSPSC :
12352203
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

100

Conjugué

unconjugated

Forme d'anticorps

affinity isolated antibody

Type de produit anticorps

primary antibodies

Clone

polyclonal

Forme

buffered aqueous solution

Poids mol.

~28 kDa

Espèces réactives

rat, mouse, human

Concentration

1 mg/mL

Technique(s)

western blot: 1:500-1:1000

Isotype

IgG

Séquence immunogène

(P-L-SP-Y-P)

Numéro d'accès NCBI

NP_008839.2

Numéro d'accès UniProt

P63000

Conditions d'expédition

wet ice

Température de stockage

−20°C

Modification post-traductionnelle de la cible

phosphorylation (pSer71)

Informations sur le gène

human ... RAC1(5879)

Immunogène

Peptide sequence around phosphorylation site of serine 71 (P-L-S(p)-Y-P), according to the protein RAC1.

Caractéristiques et avantages

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Description de la cible

Rac1 encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

Forme physique

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

10 - Combustible liquids

Classe de danger pour l'eau (WGK)

WGK 1

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

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Certificats d'analyse (COA)

Lot/Batch Number
871511203

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Consulter la Bibliothèque de documents

Ramesh Rijal et al.
Molecular biology of the cell, 30(2), 242-255 (2018-11-22)
Eukaryotic chemoattraction signal transduction pathways, such as those used by Dictyostelium discoideum to move toward cAMP, use a G protein-coupled receptor to activate multiple conserved pathways such as PI3 kinase/Akt/PKB to induce actin polymerization and pseudopod formation at the front
X Zhao et al.
Osteoarthritis and cartilage, 28(5), 613-625 (2020-02-02)
Monocyte-derived macrophages, as the predominant immune cell type that is increased in inflamed synovium, play a vital role during knee osteoarthritis (KOA) progression. However, the mechanisms underlying the recruitment of circulating monocytes to osteoarthritic knees remain uncertain. Based on previous
Wei-Hong Zhao et al.
Leukemia research, 63, 28-33 (2017-11-03)
To determine the role and mechanism of EphB4 in dasatinib (DAS) resistance in advanced chronic myeloid leukemia (CML), we explored the EphB4-mediated apoptotic and matrix microenvironment pathway in human CML and K562 cell lines. Heparinized bone marrow samples were obtained

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