PZ0229

PF-03246799 hydrochloride

≥98% (HPLC)

• Synonyme(s) : 6,7,8,9-Tetrahydro-2-(phenylmethyl)-5H-pyrimido[4,5-d]azepine hydrochloride, PF-3246799 hydrochloride
• Formule empirique (notation de Hill) : C₁₅H₁₇N₃ · xHCl
• Numéro CAS: 1065114-52-4
• Poids moléculaire : 239.32 (free base basis)
• Code UNSPSC : 51111800
• ID de substance PubChem : 329823781
• Nomenclature NACRES : NA.77

Propriétés

• Niveau de qualité: 100
• Essai: ≥98% (HPLC)
• Forme: powder
• Couleur: white to beige
• Solubilité: H₂O: 20 mg/mL, clear
• Température de stockage: room temp
• Chaîne SMILES: C1(CC2=NC(CCNCC3)=C3C=N2)=CC=CC=C1.Cl
• InChI: 1S/C15H17N3.ClH/c1-2-4-12(5-3-1)10-15-17-11-13-6-8-16-9-7-14(13)18-15;/h1-5,11,16H,6-10H2;1H
• Clé InChI: ICVPRIZGSIUCOE-UHFFFAOYSA-N

Description

Actions biochimiques/physiologiques

PF-3246799 is a potent serotonin 5-HT2C receptor agonist with an EC₅₀ of 4.5 nM and minimal activity at 5-HT2A and 5-HT2B receptors. PF-3246799 had good efficacy in a preclinical canine model of stress urinary incontinence.

PF-3246799 is a potent serotonin 5-HT2C receptor agonist.

Caractéristiques et avantages

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Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable