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MAK566

Sigma-Aldrich

Acetyl Coenzyme A Assay Kit

sufficient for 100 fluorometric tests

Synonyme(s) :

Acetyl-CoA Assay Kit

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About This Item

Niveau de qualité

100

Méthode de détection

fluorometric

Maladie(s) pertinente(s)

neurological disorders; cancer

Température de stockage

−20°C

Catégories apparentées

Description générale

Acetyl-CoA (AcCoA) is an essential cofactor and carrier of acyl groups in enzymatic acetyl transfer reactions. It is the starting compound for the citric acid cycle (Kreb′s cycle). It is also a key precursor in lipid biosynthesis, and the source of all fatty acid carbons. AcCoA acts as an indicator of fat, sugar, and protein levels and shows up on the nutritional status. In lowered glucose conditions, AcCoA participates in the production of ATP. Increased AcCoA levels are observed in prostate cancer due to elevated fatty acid utilization and thus provides an additional energy source for the tumor cell growth.

Application

The Acetyl Coenzyme A Assay Kit may be used for:
Cancer Metabolism Research
Mitochondrial Metabolism Research
Neurological Research

Caractéristiques et avantages

Enhanced Sensitivity and Accuracy: Detect Acetyl-CoA (AcCoA) concentrations ranging from 20 - 1000 pmol providing precise results across a wide range of sample types.

Compatibility with High-Throughput Systems: Seamlessly integrate our kit into high-throughput handling systems, ensuring smooth operations and accurate results, enhancing efficiency in your laboratory workflow.

Convenient Data Analysis: Supportive calculator will calculate the reagents needed according to your experimental needs, and analyze your results based on your experimental data.

Click here to download a calculator excel file.

Adéquation

Suitable for measuring Acetyl-CoA in various biological samples such as cell lysates and tissues.

Principe

Acetyl-CoA concentration is determined by a coupled enzyme assay, which results in a fluorometric (λex = 340/λem = 460 nm) product, proportional to the Acetyl-CoA present. Typical sensitivities of detection for this kit are 20-1000 pmol of Acetyl CoA. This kit is a highly sensitive assay for determining Acetyl-CoA level in a variety of biological samples.

Pictogrammes

Skull and crossbonesHealth hazardCorrosion
GHS06,GHS08,GHS05

Mention d'avertissement

Danger

Mentions de danger

H300,H311,H314,H317,H334

Classification des risques

Acute Tox. 2 Oral - Acute Tox. 3 Dermal - Eye Dam. 1 - Resp. Sens. 1 - Skin Corr. 1B - Skin Sens. 1

Code de la classe de stockage

6.1A - Combustible acute toxic Cat. 1 and 2 / very toxic hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

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Certificats d'analyse (COA)

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