SMB01401

Hydroxycotinine

≥95%

• Synonyme(s) : (3′R,5′S)-3′-Hydroxycotinine, (3S-trans)-3-Hydroxycotinine, trans-3-Hydroxycotinine, Alkaloids, Metabolites, Nicotine
• Formule empirique (notation de Hill) : C₁₀H₁₂N₂O₂
• Numéro CAS: 34834-67-8
• Poids moléculaire : 192.21
• Numéro MDL: MFCD01320408
• Code UNSPSC : 12352200

Propriétés

• Source biologique: synthetic
• Niveau de qualité: 100
• Essai: ≥95%
• Forme: powder or crystals
• Couleur: white to light off-white
• Pf: 108-110 °C
• Solubilité: acetonitrile: soluble; chloroform: soluble; methanol: soluble
• Application(s): cell analysis; clinical research; general analytical; life science and biopharma; metabolomics
• Température de stockage: 2-8°C
• Chaîne SMILES: CN1[C@@H](C[C@@H](O)C1=O)C=2C=CC=NC2
• InChI: InChI=1S/C10H12N2O2/c1-12-8(5-9(13)10(12)14)7-3-2-4-11-6-7/h2-4,6,8-9,13H,5H2,1H3/t8-,9+/m0/s1
• Clé InChI: XOKCJXZZNAUIQN-DTWKUNHWSA-N

Description

Description générale

Hydroxycotinine, also known as trans-3′-Hydroxycotinine, is an alkaloid and a cotinine derivative with a hydroxy group substitution at the C-3 position (the 3R,5S-diastereomer). It is functionally related to (-)-cotinine. Hydroxycotinine is classified as an N-alkylpyrrolidine, a member of the pyridines, a pyrrolidine alkaloid, and a member of the pyrrolidin-2-ones. It is a product of CYP₂A₆ metabolism of the primary nicotine metabolite, cotinine, and serves as a biomarker of nicotine metabolism, holding significant importance in various scientific research applications.

Application

Hydroxycotinine finds application in compound screening libraries, metabolomics, biochemical, phytochemical, and drug discovery research.

Caractéristiques et avantages

Versatile and adaptable for wide variety of research and metabolomics applications.

Informations sur la sécurité

• Pictogrammes: GHS06
• Mention d'avertissement: Danger
• Mentions de danger: H301
• Conseils de prudence: P264 - P270 - P301 + P310 - P405 - P501
• Classification des risques: Acute Tox. 3 Oral
• Code de la classe de stockage: 6.1C - Combustible acute toxic Cat.3 / toxic compounds or compounds which causing chronic effects
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable