MAB2638

Anti-Integrin beta7 Antibody, clone TN114

clone TN114, from hamster(Armenian)

• Synonyme(s) : integrin, beta 7, integrin beta 7 subunit, Gut homing receptor beta subunit
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: hamster (Armenian)
• Niveau de qualité: 100
• Forme d'anticorps: purified antibody
• Type de produit anticorps: primary antibodies
• Clone: TN114, monoclonal
• Espèces réactives: human
• Technique(s): flow cytometry: suitable; immunohistochemistry: suitable; immunoprecipitation (IP): suitable
• Isotype: IgG
• Numéro d'accès NCBI: NP_000880.1
• Numéro d'accès UniProt: P26010
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ITGB7(3695)

Description

Description générale

Integrin beta7 is an adhesion molecule belonging to the integrin beta chain family. It forms heterodimers with the alpha subunit, most notably the integrin alpha4 and alphaE subunits, functioning to mediate migration and homing of lymphocytes to the gut-associated lymphoid tissue (GALT). The heterodimer formed with alpha4, α4β7, is specifically involved in the homing and migration of lymphocytes to the gut, while αEβ7 is involved in the binding of T lymphocytes to epithelial cells and is induced by TGFβ1. Integrin beta7 has been observed in several different leukocyte lines.

Spécificité

The antibody recognizes Integrin beta7.

Immunogène

Epitope: Unknown

Purified human integrin beta7 protein.

Application

Anti-Integrin beta7 Antibody, clone TN114 is an antibody against Integrin beta7 for use in FC, IP, IH.

Research Category
Cell Structure

Research Sub Category
Integrins

Qualité

Evaluated by Flow Cytometry in human PBMC′s.

Flow Cytometry Analysis: 1 µg/mL of this antibody detected Integrin beta7 on human PBMC′s.

Description de la cible

~ 86 kDa

Forme physique

Format: Purified

Protein G Purified

Purified armenian hamster monoclonal IgG in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
Human peripheral blood mononuclear cells (PBMC′s).

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable