GF440
TGF beta 2, Human
HumanKine®, recombinant, Xeno-free, >95% (SDS-PAGE), suitable for cell culture
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About This Item
Code UNSPSC :
12352202
eCl@ss :
32160405
Nomenclature NACRES :
NA.27
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Description générale
HumanKine growth factors are expressed in a proprietary human 293 protein expression system and are manufactured without the use of any animal products and are considered Xeno-Free.
Transforming Growth Factor- beta2 (TGFb2) is a member of a superfamily of homologous, disulfide-linked, homodimeric proteins that regulate the proliferation and differentiation of normal and transformed cells. TGfb2 regulates proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers.
Qualité
Bioactivity assay: Determined by the dose dependent inhibition of IL-4 induced proliferation of mouse HT-2 cells (BALB/c spleen activated by sheep erythrocytes in the presence of IL-2). ED50 is typically 0.1-0.5 ng/ml.
HumanKine TGF beta2 is manufactured using all non-animal reagents and is considered Xeno-Free
Forme physique
Product is presented in 50mM NaOAc pH 4.5 and filtered through a 0.2 micron filter before lyophilization.
Stockage et stabilité
Store at -20°C for up to 4 months from date of receipt. Further dilutions should be made into appropriate buffer or medium to which protein has been added.
Informations légales
HumanKine is a registered trademark of Proteintech Group, Inc. and Humanzyme, Inc
Clause de non-responsabilité
Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.
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