ABN354

Anti-NIPSNAP2 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Non-neuronal SNAP25-like protein 2, Glioblastoma-amplified sequence, GBAS
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human, mouse
• Technique(s): immunohistochemistry: suitable; western blot: suitable
• Numéro d'accès UniProt: O75323
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... GBAS(2631)

Description

Description générale

The NIPSNAP proteins comprise a family of evolutionarily well-conserved proteins with strong sequence similarity to the central portion of a protein encoded by C. elegans chromosome III between a 4-nitrophenylphosphatase (NIP) domain and non-neuronal SNAP25-like protein. NIPSNAP2, a novel gene encoding a protein with tyrosine phosphorylation sites and a transmembrane domain, is co-amplified with EGFR in approximately 40% of glioblastomas, the most common and malignant form of central nervous system tumors. It is widely expressed and most abundant in heart and skeletal muscle. NIPSNAP proteins have been suggested to be important in vesicular transport.

Spécificité

NIPSNAP2 antibody is predicted to not cross-react with any other members of the NIPSNAP protein family.

Immunogène

KLH-conjugated linear peptide corresponding to human NIPSNAP2.

Application

Detect the NIPSNAP2 protein using this Anti-NIPSNAP2 validated for use in WB & IHC.

Immunohistochemistry Analysis: 2.5µg/mL of this antibody from a representative lot detected NIPSNAP2 in mouse skeletal muscle tissue.

Qualité

Evaluated by Western Blot in human skeletal muscle tissue lysate.

Western Blotting Analysis: 1 µg/mL of this antibody detected NIPSNAP2 in 15 µg of human skeletal muscle tissue lysate.

Description de la cible

~31 kDa observed

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable