ABN192

Anti-ZFP36L1 Antibody

from rabbit, purified by affinity chromatography

• Synonyme(s) : Zinc finger protein 36, C3H1 type-like 1, Butyrate response factor 1, EGF-response factor 1, ERF-1, Protein TIS11B
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: affinity isolated antibody
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Produit purifié par: affinity chromatography
• Espèces réactives: human
• Réactivité de l'espèce (prédite par homologie): bovine (based on 100% sequence homology), canine (based on 100% sequence homology), horse (based on 100% sequence homology), mouse (based on 100% sequence homology), rat (based on 100% sequence homology)
• Technique(s): western blot: suitable
• Numéro d'accès NCBI: NP_001231627
• Numéro d'accès UniProt: Q07352
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... ZFP36L1(677)

Description

Description générale

As a member of the ZFP36/tristetraprolin (TTP) family of zinc finger proteins, ZFP36L1 serves as an RNA-binding protein (RBP) that is known to interact with AU-rich elements in the 3’-untranslated region of mRNAs, resulting in their degradation. It serves as a target for Keratinocyte-derived growth factors and cytokines. ZFP36L1 is reported to play an important role in various physiological processes, including wound healing, epidermal homeostasis, inflammation, erythroid differentiation, thymocyte development, and in the prevention of malignant transformation. Defects in the ZFPP36L1 gene have been implicated in Mutiple Sclerosis and cancer.

Spécificité

This antibody recognizes the C-terminus of ZFP36L1.

Immunogène

Epitope: C-terminus

KLH-conjugated linear peptide corresponding to the C-terminus of Human ZFP36L1.

Application

Anti-ZFP36L1 detects levels of ZFP36L1 proteins & has been published & validated for use in WB.

Research Category
Neuroscience

Research Sub Category
Neurodegenerative Diseases

Qualité

Evaluated by Western Blot in HeLa cell lysate.

Western Blot Analysis: 1 µg/mL of this antibody detected ZFP36L1 in 10 µg of HeLa cell lysate.

Description de la cible

~38 kDa observed

Forme physique

Affinity purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Stockage et stabilité

Stable for 1 year at 2-8°C from date of receipt.

Remarque sur l'analyse

Control
HeLa cell lysate

Autres remarques

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable