ABE43

Anti-Ebp1 NT Antibody

serum, from rabbit

• Synonyme(s) : Proliferation-associated protein 2G4, Cell cycle protein p38-2G4 homolog, hG4-1, ErbB3-binding protein 1, Cell cycle protein p38-2G4 homolog, ErbB-3 binding protein 1, ErbB3-binding protein Ebp1
• Code UNSPSC : 12352203
• eCl@ss : 32160702
• Nomenclature NACRES : NA.41

Propriétés

• Source biologique: rabbit
• Niveau de qualité: 100
• Forme d'anticorps: serum
• Type de produit anticorps: primary antibodies
• Clone: polyclonal
• Espèces réactives: mouse, rat, human
• Technique(s): immunocytochemistry: suitable; western blot: suitable
• Isotype: IgG
• Numéro d'accès NCBI: NP_006182
• Numéro d'accès UniProt: Q9UQ80
• Conditions d'expédition: wet ice
• Modification post-traductionnelle de la cible: unmodified
• Informations sur le gène: human ... PA2G4(5036)

Description

Description générale

Ebp1 is an RNA-binding protein involved in growth regulation. In cancer cells, this protein and has been implicated in growth inhibition and differentiation. Ebp1 is known to bind ribosomal and double-stranded RNA. It is a found in pre-ribosomal ribonucleoprotein complexes and is believed to play a role in ribosome assembly and rRNA processing. This protein is also a component of cytoplasmic bcl-2 messenger ribonucleoprotein. Through interactions with histion deacetylases, this protein can act transcriptional co-repressor of androgen receptor-regulated genes and other cell cycle regulatory genes. Ebp1 also interacts with the cytoplasmic domain of the ErbB3 receptor, potentially transducing regulatory growth signals.

Spécificité

Recognizes Ebp-1.

Immunogène

Epitope: N-terminus

Linear Peptide corresponding to the N-terminus of Ebp1.

Application

Anti-Ebp1 N-terminal Antibody is a Rabbit Polyclonal Antibody for detection of Ebp1 also known as Proliferation-associated protein 2G4 & has been validated in WB, ICC.

Immunocytochemistry:
A 1:500 dilution from a representative lot detected Ebp1 in NIH/3T3, A431, and HeLa cells.

Research Category
Epigenetics & Nuclear Function

Epigenetics & Nuclear Function

Research Sub Category
RNA Metabolism & Binding Proteins

Chromatin Biology

Qualité

Evaluated by Western Blotting in A431 cell lysate.

Description de la cible

48 kDa Observed

Liaison

Replaces: 07-397

Forme physique

Rabbit Polyclonal Serum with 0.05% sodium azide

Unpurified

Stockage et stabilité

Stable for 1 year at -20°C from date of receipt.
Handling Recommendations: Upon receipt and prior to removing the cap, centrifuge the vial and gently mix the solution. Aliquot into microcentrifuge tubes and store at -20°C. Avoid repeated freeze/thaw cycles, which may damage IgG and affect product performance.

Remarque sur l'analyse

Control
A431 Cell Lysate.

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Informations sur la sécurité

• Code de la classe de stockage: 12 - Non Combustible Liquids
• Classe de danger pour l'eau (WGK): WGK 1
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable