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Principaux documents

AB5052

Sigma-Aldrich

Anti-Glycine Receptor Antibody

Chemicon®, from rabbit

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About This Item

Code UNSPSC :
12352203
eCl@ss :
32160702
Nomenclature NACRES :
NA.41

Source biologique

rabbit

Niveau de qualité

Forme d'anticorps

affinity purified immunoglobulin

Type de produit anticorps

primary antibodies

Clone

polyclonal

Produit purifié par

affinity chromatography

Espèces réactives

rat, mouse, human

Fabricant/nom de marque

Chemicon®

Technique(s)

immunoprecipitation (IP): suitable
western blot: suitable

Numéro d'accès NCBI

Numéro d'accès UniProt

Conditions d'expédition

dry ice

Modification post-traductionnelle de la cible

unmodified

Informations sur le gène

human ... GLRB(2743)

Spécificité

Recognizes glycine receptor alpha1. Shows cross reactivity to glycine receptor alpha2. subunits The antibody has been used successfully in Western blot and immunoprecipitation assays with cell extracts containing recombinant human glycine receptors and with homogenates of mouse spinal cord. By Western blot the antibody recognizes a protein with a molecular weight of ~ 48 kD.

Immunogène

Peptide from the amino terminus of the human alpha1 glycine receptor subunit conjugated to KLH.

Application

Anti-Glycine Receptor Antibody detects level of Glycine Receptor & has been published & validated for use in IP & WB.
Research Category
Neuroscience
Research Sub Category
Ion Channels & Transporters
Western blot: 1:1000 using ECL

Immunoprecipitation: 1:10 following the protocol of Raymond et al., Nature (1993) 361:637-641.

Optimal working dilutions must be determined by the end user.

Forme physique

Affinity purified immunoglobulin. Lyophilized from ammonium bicarbonate (5mM) some residual salt may be present. Reconstitute with 100 μL of PBS. Contains no preservatives.

Stockage et stabilité

Maintain lyophilized material at -20°C for up to 12 months after date of receipt. After reconstitution maintain at -20°C in undiluted aliquots for up to 6 months. Avoid repeated freeze/thaw cycles.

Informations légales

CHEMICON is a registered trademark of Merck KGaA, Darmstadt, Germany

Clause de non-responsabilité

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Code de la classe de stockage

11 - Combustible Solids

Classe de danger pour l'eau (WGK)

WGK 1


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Retrouvez la documentation relative aux produits que vous avez récemment achetés dans la Bibliothèque de documents.

Consulter la Bibliothèque de documents

Differential plasticity of the GABAergic and glycinergic synaptic transmission to rat lumbar motoneurons after spinal cord injury.
Sadlaoud, K; Tazerart, S; Brocard, C; Jean-Xavier, C; Portalier, P; Brocard, F; Vinay, L; Bras, H
The Journal of Neuroscience null
K Baer et al.
Neuroscience, 122(3), 773-784 (2003-11-19)
Gephyrin is a postsynaptic clustering molecule that forms a protein scaffold to anchor inhibitory neurotransmitter receptors at the postsynaptic membrane of neurons. Gephyrin was first identified as a protein component of the glycine receptor complex and is also colocalized with
Localization of glycine receptors in the human forebrain, brainstem, and cervical spinal cord: an immunohistochemical review.
Baer K, Waldvogel HJ, Faull RL, Rees MI
Frontiers in Molecular Neuroscience null
Decreases of glycine receptor expression induced by median nerve injury in the rat cuneate nucleus contribute to NPY release and c-Fos expression.
Seu-Hwa Chen,Yi-Ju Tsai,Hsin-Ying Wang,Chi-Te Lin,Shin-Fang Li,June-Horng Lue
Life Sciences null
Y Y Liu et al.
Journal of applied physiology (Bethesda, Md. : 1985), 91(3), 1387-1395 (2001-08-18)
The pre-Bötzinger complex (PBC), thought to be the center of respiratory rhythm generation, is a cell column ventrolateral to the nucleus ambiguus. The present study analyzed its cellular and neurochemical composition in adult rats. PBC neurons were mainly oval, fusiform

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