528178

Plasminogen, EACA- and Lysine-Free, Human Plasma

• Synonyme(s) : Plasminogen, EACA- and Lysine-Free, Human Plasma, Profibrinolysin, Plasma Trypsinogen
• Numéro CAS: 9001-91-6
• Numéro MDL: MFCD00131922
• Code UNSPSC : 12352202
• Nomenclature NACRES : NA.25

Propriétés

• Description: Merck USA index - 14, 7521
• Niveau de qualité: 100
• Forme: lyophilized
• Activité spécifique: 7 units/mg protein
• Fabricant/nom de marque: Calbiochem^®
• Conditions de stockage: OK to freeze
• Solubilité: water: soluble
• Conditions d'expédition: ambient
• Température de stockage: −20°C

Description

Description générale

Native plasminogen (EACA- and lysine-free) from human plasma. Single chain glycoprotein containing 790 amino acid residues. Found in normal plasma at about 12 mg/100 ml. Inactive precursor of the serine protease plasmin. It is converted to the active protease by cleavage at Arg⁵⁶⁰.

Avertissement

Toxicity: Irritant (B)

Définition de l'unité

One unit is defined as the amount of enzyme that will hydrolyze 1 µmol of N-tosyl-Gly-Pro-Lys-pNA per min at 25°C, pH 7.8.

Forme physique

Lyophilized from 20 mM sodium phosphate buffer, 10 mg D-mannitol, 10 mg NaCl.

Notes préparatoires

Prepared from plasma that has been shown by certified tests to be negative for HBsAg and for antibodies to HIV and HCV.

Reconstitution

Following reconstitution, aliquot and freeze (-20°C) for long-term storage or refrigerate (4°C) for short-term storage. Stock solutions are stable for at least 1 week at 4°C or for 1-2 months at -20°C.

Autres remarques

Sun, Z., et al. 2002. Biochim. Biophys. Acta1596, 182.
Robbins, K.C., et al. 1967. J. Biol. Chem.242, 2333.

Informations légales

CALBIOCHEM is a registered trademark of Merck KGaA, Darmstadt, Germany

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3