940674

DBCO-NHCO-PEG4-amine TFA

≥95%

• Synonyme(s) : 15-Amino-N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl]-4,7,10,13-tetraoxapentadecanamide, 4,7,10,13-Tetraoxapentadecanamide, 15-amino-N-[3-(11,12-didehydrodibenz[b,f]azocin-5(6H)-yl)-3-oxopropyl], ADIBO-PEG4-amine TFA
• Formule empirique (notation de Hill) : C₂₉H₃₇N₃O₆ · xC₂HF₃O₂
• Numéro CAS: 1255942-08-5
• Poids moléculaire : 523.62 (free base basis)
• Numéro MDL: MFCD28334576
• Code UNSPSC : 12352200

Propriétés

• Niveau de qualité: 100
• Essai: ≥95%
• Forme: solid
• Couleur: colorless to yellow-brown
• Température de stockage: −20°C
• Chaîne SMILES: O=C(NCCC(=O)N1C=2C=CC=CC2C#CC=3C=CC=CC3C1)CCOCCOCCOCCOCCN
• InChI: 1S/C29H37N3O6.C2HF3O/c30-13-16-36-18-20-38-22-21-37-19-17-35-15-12-28(33)31-14-11-29(34)32-23-26-7-2-1-5-24(26)9-10-25-6-3-4-8-27(25)32;3-2(4,5)1-6/h1-8H,11-23,30H2,(H,31,33);1H
• Clé InChI: MRRSYYMIRSTYMO-UHFFFAOYSA-N

Description

Application

DBCO-PEG4-Amine TFA is a heterobifunctional building block with two reactive terminals. The Dibenzocyclooctyne (DBCO) terminus is useful for copper-free click chemistry. DBCO compounds react with azides without need of Cu(I) catalyst due to the strained nature of alkyne resulting in formation of fast and stable triazole linkage. The amine terminus is useful for reaction with carboxylic acid containing linkers in presence in actiavtors such as EDC or HATU.

Caractéristiques et avantages

The PEG4 linker is suited for improving solubility of resulting conjugates and provides sufficient length to minimize interactions between macromolecules of interest.

Informations sur la sécurité

• Code de la classe de stockage: 11 - Combustible Solids
• Classe de danger pour l'eau (WGK): WGK 3
• Point d'éclair (°F): Not applicable
• Point d'éclair (°C): Not applicable