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Principaux documents

279633

Sigma-Aldrich

p-Xylylenediamine

99%

Synonyme(s) :

1,4-Bis(aminomethyl)benzene, α,α′-Diamino-p-xylene

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About This Item

Formule linéaire :
C6H4(CH2NH2)2
Numéro CAS:
Poids moléculaire :
136.19
Beilstein:
2206190
Numéro CE :
Numéro MDL:
Code UNSPSC :
12162002
ID de substance PubChem :
Nomenclature NACRES :
NA.23

Essai

99%

Forme

solid

pb

230 °C/10 mmHg (lit.)

Pf

60-63 °C (lit.)

Chaîne SMILES 

NCc1ccc(CN)cc1

InChI

1S/C8H12N2/c9-5-7-1-2-8(6-10)4-3-7/h1-4H,5-6,9-10H2

Clé InChI

ISKQADXMHQSTHK-UHFFFAOYSA-N

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Description générale

p-Xylylenediamine (p-XDA) is an aromatic diamine monomer characterized by its two primary amino groups and rigid aromatic structure, which contribute to its exceptional thermal stability and mechanical strength. Its reactivity allows for versatile functionalization and effective cross-linking, making it a suitable building block in polymer synthesis. p-XDA′s solubility in organic solvents facilitates its incorporation into various formulations, including hydrogels for drug delivery systems.

Application

p-Xylylenediamine can be used:
  • As a monomer to synthesize ultra heat-resistant thermoplastic polyamide elastomers suitable for high-temperature applications. It contributes to increased tensile strength, toughness, and Young′s modulus of the elastomer, thereby enhancing its overall mechanical strength.
  • As a cross-linking agent to prepare solvent resistant high performance nanofiltration membranes. p-Xylylenediamine facilitates superior separation performance and stability for N,N-dimethylformamide (DMF) solution.
  • As a dendrimer core to synthesize stimuli responsive nanocarriers for cancer drug delivery.
  • As a capping agent to prepare fluorescent organic–inorganic hybrid CH3NH3PbBr3 nanocrystals to fabricate 3D-printed paper-based microfluidic optical sensor for naked-eye detection of picric acid.

Pictogrammes

Corrosion

Mention d'avertissement

Danger

Mentions de danger

Classification des risques

Skin Corr. 1B

Code de la classe de stockage

8A - Combustible corrosive hazardous materials

Classe de danger pour l'eau (WGK)

WGK 3

Point d'éclair (°F)

Not applicable

Point d'éclair (°C)

Not applicable

Équipement de protection individuelle

Eyeshields, Faceshields, Gloves, type P3 (EN 143) respirator cartridges


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Consulter la Bibliothèque de documents

Shuai Yuan et al.
Advanced materials (Deerfield Beach, Fla.), 31(44), e1904319-e1904319 (2019-09-19)
Compared to efficient green and near-infrared light-emitting diodes (LEDs), less progress has been made on deep-blue perovskite LEDs. They suffer from inefficient domain [various number of PbX6- layers (n)] control, resulting in a series of unfavorable issues such as unstable
Weiqiang Zhan et al.
Journal of medicinal chemistry, 50(23), 5655-5664 (2007-10-26)
In light of a proposed molecular mechanism for the C-X-C chemokine receptor type 4 (CXCR4) antagonist 1 (AMD3100), a template with the general structure 2 was designed, and 15 was identified as a lead by means of an affinity binding
Choon Young Lee et al.
Bioorganic & medicinal chemistry letters, 19(22), 6326-6330 (2009-10-14)
Three dendritic polyphenols (generation 1) were synthesized: a syringaldehyde-based dendrimer (1), a vanillin-based dendrimer (2), and an iodinated vanillin-based dendrimer (3). They all showed strong antioxidant activity according to the 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical assay. The syringaldehyde dendrimer was twice and
Francesc Yraola et al.
Journal of medicinal chemistry, 49(21), 6197-6208 (2006-10-13)
Structure activity relationships for semicarbazide-sensitive amine oxidase/vascular adhesion protein-1 (SSAO/VAP-1) were studied using a library of arylalkylamine substrates, with the aim of contributing to the discovery of more efficient SSAO substrates. Experimental data were contrasted with computational docking studies, thereby

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