SBR00092

Temocillin Disodium

≥80% (HPLC), powder

• Synonym(s): Ipconazole
• Empirical Formula (Hill Notation): C₁₆H₁₆N₂Na₂O₇S₂
• CAS Number: 61545-06-0
• Molecular Weight: 458.42
• UNSPSC Code: 51101500

Properties

• Quality Level: 100
• Assay: ≥80% (HPLC)
• form: powder
• color: white to yellow
• antibiotic activity spectrum: Gram-negative bacteria
• Mode of action: cell wall synthesis | inhibits
• shipped in: ambient
• storage temp.: 2-8°C
• SMILES string: CC1([C@@H](N2[C@H](S1)[C@@](C2=O)(NC(=O)C(C3=CSC=C3)C(=O)O)OC)C(=O)O)C
• InChI: 1S/C18H24ClN3O/c1-13(2)17-8-5-15(9-14-3-6-16(19)7-4-14)18(17,23)10-22-12-20-11-21-22/h3-4,6-7,11-13,15,17,23H,5,8-10H2,1-2H3
• InChI key: QTYCMDBMOLSEAM-UHFFFAOYSA-N

Description

General description

Temocillin disodium is an aminoglycoside antibiotic which inhibits protein synthesis.

Biochem/physiol Actions

Temocillin Disodium inhibits bacterial cell wall synthesis, which is necessary for the growth and survival of bacterial cells. Specifically, it interferes with the synthesis of peptidoglycan, the major component of the bacterial cell wall, by binding to a specific target on the cell wall synthesis enzyme called penicillin-binding protein 3 (PBP3). This blocks the synthesis of peptidoglycan, leading to the weakening and eventual lysis of the bacterial cell.

Safety Information

• Pictograms: GHS08
• Signal Word: Danger
• Hazard Statements: H317,H334
• Precautionary Statements: P261 - P272 - P280 - P284 - P302 + P352 - P333 + P313
• Hazard Classifications: Resp. Sens. 1 - Skin Sens. 1
• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable