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Merck

HIRA

histone cell cycle regulator

동의어:
DGCR1, TUP1, TUPLE1
:
UniProtKB ID:
Clone ID:
  • Human(7290) Summary: This gene encodes a histone chaperone that preferentially places the variant histone H3.3 in nucleosomes. Orthologs of this gene in yeast, flies, and plants are necessary for the formation of transcriptionally silent heterochomatin. This gene plays an important role in the formation of the senescence-associated heterochromatin foci. These foci likely mediate the irreversible cell cycle changes that occur in senescent cells. It is considered the primary candidate gene in some haploinsufficiency syndromes such as DiGeorge syndrome, and insufficient production of the gene may disrupt normal embryonic development. [provided by RefSeq, Jul 2008]
  • Mouse(15260) histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Rat(363849) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Zebrafish(568076) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • fruit fly(31680) CG12153 gene product from transcript CG12153-RA
  • cow(511514) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Horse(100052845) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • domestic cat(101098170) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • dog(486424) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Thale Cress(823578) protein HIRA
  • chicken(374074) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • sheep(101120607) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)
  • Domestic Rabbit(100352472) HIR histone cell cycle regulation defective homolog A (S. cerevisiae)

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Antibodies

제품 번호
설명
종별 반응성
응용분야
Anti-HIRA antibody produced in mouse, IgG fraction of antiserum, buffered aqueous solution,
종별 반응성
human
응용분야
immunofluorescence
western blot
Anti-HIRA Antibody, clone 6Q7Y6, Rabbit Monoclonal, ,
종별 반응성
human
응용분야
western blot
Anti-HIRA Antibody, clone WC119, clone WC119, from mouse,
종별 반응성
human, mouse
응용분야
immunoprecipitation (IP)
western blot
Anti-HIRA (center) antibody produced in rabbit, saturated ammonium sulfate (SAS) precipitated, buffered aqueous solution,
종별 반응성
human
응용분야
ELISA
western blot
Anti- HIRA antibody produced in rabbit, ,
종별 반응성
human, mouse
응용분야
immunohistochemistry
western blot

esiRNA

제품 번호
설명
MISSION® esiRNA, targeting mouse Hira,
mouse
MISSION® esiRNA, targeting human HIRA, C22ORF39,
human