HDAC1
histone deacetylase 1
Synonyms:
GON-10, HD1, RPD3, RPD3L1
Species:
Human HDAC1 (3065), Mouse Hdac1 (433759), Rat Hdac1 (297893), Zebrafish hdac1 (192302), chicken HDAC1 (373961), dog HDAC1 (487309), domestic cat HDAC1 (101099228), cow HDAC1 (404126), domestic guinea pig Hdac1 (100728529), naked mole-rat Hdac1 (101715102)
UniProtKB ID:
Gene ID:
- Human(3065) Summary: Histone acetylation and deacetylation, catalyzed by multisubunit complexes, play a key role in the regulation of eukaryotic gene expression. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family and is a component of the histone deacetylase complex. It also interacts with retinoblastoma tumor-suppressor protein and this complex is a key element in the control of cell proliferation and differentiation. Together with metastasis-associated protein-2, it deacetylates p53 and modulates its effect on cell growth and apoptosis. [provided by RefSeq, Jul 2008]
- Mouse(433759) histone deacetylase 1
- Rat(297893) histone deacetylase 1
- Zebrafish(192302) histone deacetylase 1
- chicken(373961) histone deacetylase 1
- dog(487309) histone deacetylase 1
- domestic cat(101099228) histone deacetylase 1
- cow(404126) histone deacetylase 1
- domestic guinea pig(100728529) histone deacetylase 1
- naked mole-rat(101715102) histone deacetylase 1
- sheep(100820752) histone deacetylase 1
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Activity Assay
Product Number
Description
Species
Histone Deacetylase Assay Kit, Fluorometric, sufficient for 100 assays (96 well plates),
Species
human
Small Molecule - Antagonist
Antibodies
Product Number
Description
Species Reactivity
Application
Anti- HDAC1 antibody produced in rabbit, ,
Species Reactivity
human, mouse, rat
Application
immunohistochemistry
western blot
western blot
Anti-HDAC1 Antibody, clone 2E10, clone 2E10, Upstate®, from mouse,
Species Reactivity
human, mouse
Application
immunoprecipitation (IP)
western blot
western blot
Anti-HDAC1 Antibody, Upstate®, from rabbit,
Species Reactivity
human, mouse, rat
Application
activity assay
immunocytochemistry
immunoprecipitation (IP)
western blot
immunocytochemistry
immunoprecipitation (IP)
western blot
Small Molecule - Inhibitor
Proteins
Product Number
Description
Species
HDAC 1 from Plasmodium falciparum, recombinant, expressed in baculovirus infected insect cells, ≥40% (SDS-PAGE),
Species
esiRNA
Product Number
Description
Species