DENND1A
DENN/MADD domain containing 1A
Synonyms:
FAM31A, KIAA1608, RP11-230L22.3
Species:
Human DENND1A (57706), Mouse Dennd1a (227801), Rat Dennd1a (311913), Zebrafish dennd1a (556150), chicken DENND1A (417102), dog DENND1A (609706), domestic cat DENND1A (101088373), cow DENND1A (514134), Horse DENND1A (100067362), sheep DENND1A (101113668) ...More
UniProtKB ID:
Gene ID:
- Human(57706) Summary: Clathrin (see MIM 118955)-mediated endocytosis is a major mechanism for internalization of proteins and lipids. Members of the connecdenn family, such as DENND1A, function as guanine nucleotide exchange factors (GEFs) for the early endosomal small GTPase RAB35 (MIM 604199) and bind to clathrin and clathrin adaptor protein-2 (AP2; see MIM 601024). Thus, connecdenns link RAB35 activation with the clathrin machinery (Marat and McPherson, 2010 [PubMed 20154091]
- Mouse(227801) DENN/MADD domain containing 1A
- Rat(311913) DENN/MADD domain containing 1A
- Zebrafish(556150) DENN/MADD domain containing 1A
- chicken(417102) DENN/MADD domain containing 1A
- dog(609706) DENN/MADD domain containing 1A
- domestic cat(101088373) DENN/MADD domain containing 1A
- cow(514134) DENN/MADD domain containing 1A
- Horse(100067362) DENN/MADD domain containing 1A
- sheep(101113668) DENN/MADD domain containing 1A
- Domestic Rabbit(100340700) DENN/MADD domain containing 1A
- naked mole-rat(101722066) DENN/MADD domain containing 1A
- domestic guinea pig(100735930) DENN/MADD domain containing 1A
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Antibodies
Product Number
Description
Species Reactivity
Application
Anti-DENND1A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
bovine, dog, guinea pig, human, rabbit, rat
Application
western blot
Anti-DENND1A antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rabbit
Application
western blot