Skip to Content
Merck

CXCL12

chemokine (C-X-C motif) ligand 12

Synonyms:
IRH, PBSF, SCYB12, SDF1, TLSF, TPAR1
Species:
Human CXCL12 (6387), Mouse Cxcl12 (20315), Rat Cxcl12 (24772), chicken CXCL12 (395180), cow CXCL12 (613811), dog CXCL12 (449622), domestic cat CXCL12 (493806), domestic guinea pig Cxcl12 (100721137), sheep CXCL12 (101121145)
UniProtKB ID:
P48061, B2R4G0, E7EVL0, Q2L985, Q2L986, Q2L988, Q5IT36, Q6ICW0
Gene ID:
  • Human(6387) Summary: This gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2013]
  • Mouse(20315) chemokine (C-X-C motif) ligand 12
  • Rat(24772) chemokine (C-X-C motif) ligand 12
  • chicken(395180) chemokine (C-X-C motif) ligand 12
  • cow(613811) chemokine (C-X-C motif) ligand 12
  • dog(449622) chemokine (C-X-C motif) ligand 12
  • domestic cat(493806) chemokine (C-X-C motif) ligand 12
  • domestic guinea pig(100721137) chemokine (C-X-C motif) ligand 12
  • sheep(101121145) chemokine (C-X-C motif) ligand 12

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
AB1868P
Anti-Stromal Cell-Derived Factor-1α Antibody, Chemicon®, from rabbit,
Species Reactivity
human
Application
ELISA
neutralization
western blot
ZRB2474
Anti-CXCL12/SDF1 Antibody, clone 5I2 ZooMAb® Rabbit Monoclonal, recombinant, expressed in HEK 293 cells,
Species Reactivity
human, mouse
Application
flow cytometry
immunocytochemistry
immunohistochemistry
western blot
MABC184
Anti-SDF-1 Antibody, clone K15C, Azide free, clone K15C, from mouse,
Species Reactivity
human, mouse
Application
ELISA
immunohistochemistry
neutralization
western blot

Proteins

Product Number
Description
Species
S1577
Stromal Cell-Derived Factor 1α/pre-B Cell Growth Stimulating Factor human, recombinant, expressed in E. coli, lyophilized powder, ≥97% (SDS-PAGE), suitable for cell culture,
Species
human

esiRNA

Product Number
Description
Species
EHU129521
MISSION® esiRNA, targeting human CXCL12,
Species
human
EMU076711
MISSION® esiRNA, targeting mouse Cxcl12,
Species
mouse