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CBX3

chromobox homolog 3

Synonyms:
HECH, HP1-GAMMA, HP1Hs-gamma
Species:
UniProtKB ID:
Gene ID:
  • Human(11335) Summary: At the nuclear envelope, the nuclear lamina and heterochromatin are adjacent to the inner nuclear membrane. The protein encoded by this gene binds DNA and is a component of heterochromatin. This protein also can bind lamin B receptor, an integral membrane protein found in the inner nuclear membrane. The dual binding functions of the encoded protein may explain the association of heterochromatin with the inner nuclear membrane. This protein binds histone H3 tails methylated at Lys-9 sites. This protein is also recruited to sites of ultraviolet-induced DNA damage and double-strand breaks. Two transcript variants encoding the same protein but differing in the 5' UTR, have been found for this gene.[provided by RefSeq, Mar 2011]
  • Mouse(12417) chromobox 3
  • Rat(297093) chromobox homolog 3
  • naked mole-rat(101714000) chromobox homolog 3
  • domestic guinea pig(100714020) chromobox homolog 3
  • sheep(101106931) chromobox homolog 3
  • chicken(395355) chromobox homolog 3
  • dog(482015) chromobox homolog 3
  • cow(539788) chromobox homolog 3
  • domestic cat(101099363) chromobox homolog 3

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

    Shop the largest, most validated shRNA collection and build your own clone sets.

  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
Rabbit anti-CBX3 Antibody, Affinity Purified, Powered by Bethyl Laboratories, Inc.,
Species Reactivity
human
Application
immunohistochemistry
immunoprecipitation (IP)
Anti-phospho-HP1 γ (Ser83) Antibody, Upstate®, from rabbit,
Species Reactivity
human
Application
western blot
Anti-HP1γ Antibody, clone 14D3.1, clone 14D3.1, from mouse,
Species Reactivity
human, mouse, nonhuman primates, rat
Application
immunocytochemistry
western blot
Anti-Phospho-CBX3-S83 antibody produced in rabbit, ,
Species Reactivity
human
Application
western blot
Monoclonal Anti-CBX3 antibody produced in mouse, clone 1G12-1D9, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
immunofluorescence

western blot

esiRNA

Product Number
Description
Species
MISSION® esiRNA, targeting mouse CBX3-PS2, CBX3-PS5,
Species
mouse
MISSION® esiRNA, targeting mouse Cbx3,
Species
mouse
MISSION® esiRNA, targeting human CBX3,
Species
human
MISSION® esiRNA, targeting mouse Ensmusg00000059647,
Species
mouse