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Merck

BCL2L2

BCL2-like 2

Synonyms:
BCL-W, BCL2-L-2, BCLW, PPP1R51
Species:
Human BCL2L2 (599), Mouse Bcl2l2 (12050), Rat Bcl2l2 (60434), domestic cat BCL2L2 (768265), cow BCL2L2 (767601), dog BCL2L2 (490611)
UniProtKB ID:
Q92843, A8K0F4, Q2M3U0, Q5U0H4
Gene ID:
  • Human(599) Summary: This gene encodes a member of the BCL-2 protein family. The proteins of this family form hetero- or homodimers and act as anti- and pro-apoptotic regulators. Expression of this gene in cells has been shown to contribute to reduced cell apoptosis under cytotoxic conditions. Studies of the related gene in mice indicated a role in the survival of NGF- and BDNF-dependent neurons. Mutation and knockout studies of the mouse gene demonstrated an essential role in adult spermatogenesis. Alternative splicing results in multiple transcript variants. Read-through transcription also exists between this gene and the neighboring downstream PABPN1 (poly(A) binding protein, nuclear 1) gene. [provided by RefSeq, Dec 2010]
  • Mouse(12050) BCL2-like 2
  • Rat(60434) Bcl2-like 2
  • domestic cat(768265) BCL2-like 2
  • cow(767601) BCL2-like 2
  • dog(490611) BCL2-like 2

Custom & Knockdown Gene Products

  • siRNA

    Shop predesigned siRNA that are designed using the proprietary Rosetta Inpharmatics algorithm.

  • shRNA

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  • Custom Gene Products

    We offer a comprehensive portfolio of DNA oligos, RNA oligos and predesigned primers.

Antibodies

Product Number
Description
Species Reactivity
Application
SAB1401027
Anti-BCL2L2 antibody produced in mouse, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
western blot
SAB1402702
Monoclonal Anti-BCL2L2 antibody produced in mouse, clone 2E4, purified immunoglobulin, buffered aqueous solution,
Species Reactivity
human
Application
ELISA
western blot
SAB4502627
Anti-BCLW antibody produced in rabbit, affinity isolated antibody,
Species Reactivity
human, mouse, rat
Application
ELISA
immunofluorescence
western blot

Proteins

Product Number
Description
Species
B1059
Bcl-w (Minus C-Terminus) human, >95% (SDS-PAGE), recombinant, expressed in E. coli, buffered aqueous glycerol solution,
Species
human

esiRNA

Product Number
Description
Species
EHU058421
MISSION® esiRNA, targeting human BCL2L2,
Species
human
EMU021461
MISSION® esiRNA, targeting mouse Bcl2l2,
Species
mouse