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AKAP12

A kinase (PRKA) anchor protein 12

Synonymes:
AKAP250, SSeCKS
Espèce(s):
ID UniProtKB:
ID du gène:
  • Human(9590) Summary: The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is expressed in endothelial cells, cultured fibroblasts, and osteosarcoma cells. It associates with protein kinases A and C and phosphatase, and serves as a scaffold protein in signal transduction. This protein and RII PKA colocalize at the cell periphery. This protein is a cell growth-related protein. Antibodies to this protein can be produced by patients with myasthenia gravis. Alternative splicing of this gene results in two transcript variants encoding different isoforms. [provided by RefSeq, Jul 2008]
  • Mouse(83397) A kinase (PRKA) anchor protein (gravin) 12
  • Rat(83425) A kinase (PRKA) anchor protein 12
  • sheep(101105509) A kinase (PRKA) anchor protein 12
  • domestic guinea pig(100733313) A kinase (PRKA) anchor protein 12
  • naked mole-rat(101719181) A kinase (PRKA) anchor protein 12
  • chicken(421634) A kinase (PRKA) anchor protein 12
  • dog(476246) A kinase (PRKA) anchor protein 12
  • Horse(100063263) A kinase (PRKA) anchor protein 12
  • cow(513774) A kinase (PRKA) anchor protein 12
  • domestic cat(101083007) A kinase (PRKA) anchor protein 12

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Antibodies

Référence du produit
Description
Espèces réactives
Application
Anti-AKAP12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry

western blot
Anti-AKAP12 antibody produced in rabbit, Prestige Antibodies® Powered by Atlas Antibodies, affinity isolated antibody, buffered aqueous glycerol solution,
Espèces réactives
human
Application
immunofluorescence
immunohistochemistry
Anti-phospho AKAP-12/Gravin Antibody (Thr766), serum, from rabbit,
Espèces réactives
human, rat, rhesus macaque
Application
immunocytochemistry
western blot
Anti-SSeCKS antibody produced in sheep, IgG fraction of antiserum, buffered aqueous solution,
Espèces réactives
rat
Application
immunoprecipitation (IP)
western blot
Anti-AKAP12 antibody produced in rabbit, affinity isolated antibody,
Espèces réactives
human
Application
ELISA
immunofluorescence

immunohistochemistry

esiRNA

Référence du produit
Description
Espèce(s)
MISSION® esiRNA, targeting mouse Akap12,
Espèce(s)
mouse
MISSION® esiRNA, targeting human AKAP12,
Espèce(s)
human