8.52118

Fmoc-Asp(EDANS)-OH

Novabiochem^®

• Synonym(s): Fmoc-Asp(EDANS)-OH
• Empirical Formula (Hill Notation): C₃₁H₂₉N₃O₈S
• CAS Number: 182253-73-2
• Molecular Weight: 603.64
• MDL number: MFCD02094140
• UNSPSC Code: 12352209

Properties

• Quality Level: 200
• product line: Novabiochem^®
• Assay: ≥95.0% (HPLC); ≥98% (TLC)
• form: powder
• reaction suitability: reaction type: Fmoc solid-phase peptide synthesis
• manufacturer/tradename: Novabiochem^®
• application(s): peptide synthesis
• functional group: Fmoc
• storage temp.: 15-25°C
• SMILES string: [S](=O)(=O)(O)c1c2c(c(ccc2)NCCNC(=O)C[C@H](NC(=O)OCC3c4c(cccc4)c5c3cccc5)C(=O)O)ccc1
• InChI: 1S/C31H29N3O8S/c35-29(33-16-15-32-26-13-5-12-24-23(26)11-6-14-28(24)43(39,40)41)17-27(30(36)37)34-31(38)42-18-25-21-9-3-1-7-19(21)20-8-2-4-10-22(20)25/h1-14,25,27,32H,15-18H2,(H,33,35)(H,34,38)(H,36,37)(H,39,40,41)/t27-/m0/s1
• InChI key: ZHXKVZRMHMFRBQ-MHZLTWQESA-N

Description

General description

Fluorescence-labeled amino acid for preparing fluorescence-quenched peptide substrates by Fmoc SPPS ^[1]. Most frequently used in conjunction with Dabcyl quenching group.

Associated Protocols and Technical Articles
Cleavage and Deprotection Protocols for Fmoc SPPS
Chromogenic Labeling of Synthetic Peptides

Literature references

^[1] L. L. Maggiora, et al. (1992) J. Med. Chem., 35, 3727.

Linkage

Replaces: 04-12-1288

Analysis Note

Color (visual): grey
Appearance of substance (visual): powder
Identity (IR): passes test
Enantiomeric purity: ≥ 99.5 % (a/a)
Purity (TLC(CMA1)): ≥ 98 %
Assay (HPLC, area%): ≥ 95.0 % (a/a)

To see the solvent systems used for TLC of Novabiochem^® products please click here.

Legal Information

Novabiochem is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 2
• Flash Point(F): Not applicable
• Flash Point(C): Not applicable