SML4121
Erythrodiol
≥98% (HPLC)
Synonym(s):
3β-Erythrodiol, Oleanolic alcohol, (3β)-Olean-12-ene-3,28-diol, Olean-12-ene-3β,28-diol, (+)-Erythrodiol, 3β,28-Dihydroxyolean-12-ene
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About This Item
Empirical Formula (Hill Notation):
C30H50O2
CAS Number:
Molecular Weight:
442.72
UNSPSC Code:
12352200
Quality Level
assay
≥98% (HPLC)
form
powder
color
white to beige
solubility
DMSO: 2 mg/mL, clear (Warmed)
storage temp.
-10 to -25°C
Biochem/physiol Actions
Natural pentacyclic triterpenoid that exhibits anti-inflammatory, antioxidant, and antitumor properties, and enhances cholesterol efflux.
Erythrodiol, also known as Oleanolic alcohol, is a natural triterpene found in olive oil and other plants, known for its multi-faceted pharmacological actions. It displays anti-inflammatory effects by inhibiting pro-inflammatory cytokines and modulating enzymes involved in inflammation. As an antioxidant, it scavenges free radicals, mitigating oxidative stress. In addition, erythrodiol exhibits antitumor properties through antiproliferative activities like inducing cancer cell apoptosis and cell cycle arrest. Erythrodiol also enhances cholesterol efflux in macrophages by increasing the half-life of the ATP-binding cassette transporter A1 (ABCA1) protein, primarily by preventing its degradation.
Erythrodiol, also known as Oleanolic alcohol, is a natural triterpene found in olive oil and other plants, known for its multi-faceted pharmacological actions. It displays anti-inflammatory effects by inhibiting pro-inflammatory cytokines and modulating enzymes involved in inflammation. As an antioxidant, it scavenges free radicals, mitigating oxidative stress. In addition, erythrodiol exhibits antitumor properties through antiproliferative activities like inducing cancer cell apoptosis and cell cycle arrest. Erythrodiol also enhances cholesterol efflux in macrophages by increasing the half-life of the ATP-binding cassette transporter A1 (ABCA1) protein, primarily by preventing its degradation.
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