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SML1472

Sigma-Aldrich

TNIIIA2 trifluoroacetate salt

≥95% (HPLC)

Synonym(s):

L-Arginyl-L-seryl-L-threonyl-L-α-aspartyl-L-leucyl-L-prolylglycyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-L-threonyl-L-histidyl-L-tyrosyl-L-threonyl-L-isoleucyl-L-threonyl-L-isoleucyl-L-arginylglycyl-L-valyl-L-cysteine trifluoroacetate salt, RSTDLPGLKAATHYTITIRGVC trifluoroacetate salt

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About This Item

Empirical Formula (Hill Notation):
C103H173N31O31S · xC2HF3O2
CAS Number:
Molecular Weight:
2373.73 (free base basis)
UNSPSC Code:
41106514
NACRES:
NA.77

Quality Level

assay

≥95% (HPLC)

form

film

storage condition

desiccated

color

colorless

shipped in

wet ice

storage temp.

−20°C

Biochem/physiol Actions

TNIIIA2 is a Tenascin-C driven proadhesive peptide that potently activates β1-integrins including α5β1. TNIIIA2 forces hematopoietic tumor cell lines to adhere via VLA-4 to fibronectin, which induces apoptosis. It appears that TNIIIA2 uses Syndecan-4 as a receptor.
TNIIIA2 is a potent activator of β1-integrins including α5β1

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable


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