SML1472

TNIIIA2 trifluoroacetate salt

≥95% (HPLC)

• Synonym(s): L-Arginyl-L-seryl-L-threonyl-L-α-aspartyl-L-leucyl-L-prolylglycyl-L-leucyl-L-lysyl-L-alanyl-L-alanyl-L-threonyl-L-histidyl-L-tyrosyl-L-threonyl-L-isoleucyl-L-threonyl-L-isoleucyl-L-arginylglycyl-L-valyl-L-cysteine trifluoroacetate salt, RSTDLPGLKAATHYTITIRGVC trifluoroacetate salt
• Empirical Formula (Hill Notation): C₁₀₃H₁₇₃N₃₁O₃₁S · xC₂HF₃O₂
• CAS Number: 876594-05-7
• Molecular Weight: 2373.73 (free base basis)
• UNSPSC Code: 41106514
• NACRES: NA.77

Properties

• Quality Level: 100
• assay: ≥95% (HPLC)
• form: film
• storage condition: desiccated
• color: colorless
• shipped in: wet ice
• storage temp.: −20°C

Description

Biochem/physiol Actions

TNIIIA2 is a Tenascin-C driven proadhesive peptide that potently activates β1-integrins including α5β1. TNIIIA2 forces hematopoietic tumor cell lines to adhere via VLA-4 to fibronectin, which induces apoptosis. It appears that TNIIIA2 uses Syndecan-4 as a receptor.

TNIIIA2 is a potent activator of β1-integrins including α5β1

Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable