SMB01013

Methyl 2,5-Dihydroxycinnamate

≥90% (LC/MS-ELSD)

• Synonym(s): 2,4-Dihydroxymethylcinnamate, Methyl grevillate
• Empirical Formula (Hill Notation): C₁₀H₁₀O₄
• CAS Number: 123064-80-2
• Molecular Weight: 194.18
• MDL number: MFCD00132932
• UNSPSC Code: 12352205
• NACRES: NA.25

Properties

• biological source: plant
• assay: ≥90% (LC/MS-ELSD)
• form: solid
• mol wt: 194.18
• solubility: water: slightly soluble
• application(s): metabolomics; vitamins, nutraceuticals, and natural products
• storage temp.: −20°C
• SMILES string: O(C)C(=O)C=Cc1c(ccc(c1)O)O
• InChI: 1S/C10H10O4/c1-14-10(13)5-2-7-6-8(11)3-4-9(7)12/h2-6,11-12H,1H3
• InChI key: BQCNSTFWSKOWMA-UHFFFAOYSA-N

Description

General description

Methyl 2,5-dihydroxycinnamate, a hydroxycinnamic acid, is a bioactive natural compound commonly derived from plants like Azadirachta indica and Murraya paniculata. Current research indicates that this plant-derived metabolite may possess diverse biological activities, encompassing anti-inflammatory and antitumor properties. Furthermore, it serves as a human urinary metabolite, a geroprotector, and an inhibitor of EC 2.7.10.1 (receptor protein-tyrosine kinase). It is a cell-permeable analog of erbstatin, a natural substance found in Streptomyces, demonstrates inhibitory effects on the autophosphorylation of the epidermal growth factor receptor. Moreover, it acts as a competitive inhibitor of epidermal growth factor receptor-associated tyrosine kinase, effectively impeding v-abl tyrosine kinase activation. Additionally, Methyl 2,5-dihydroxycinnamate has been observed to induce apoptosis in mouse thymocytes and inhibit the G2/M phase of the cell cycle.

Application

Methyl 2,5-Dihydroxycinnamate is a natural product derived from plant source that finds application in compound screening libraries, metabolomics, phytochemical, and pharmaceutical research.

Features and Benefits

• Suitable for Biochemical and Biomedical research
• Versatile and adaptable for wide variety of laboratory and research applications

Other Notes

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Safety Information

• Storage Class: 11 - Combustible Solids
• wgk_germany: WGK 3
• flash_point_f: Not applicable
• flash_point_c: Not applicable