SAB5702877

Anti-KDM4B/JMJD2B Antibody, clone 8I0I1, Rabbit Monoclonal

• Synonym(s): JMJD2B, TDRD14B
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 8I0I1, monoclonal
• form: liquid
• mol wt: 150 kDa
• species reactivity: human, rat, rat
• concentration: 1.5 mg/mL
• technique(s): ChIP: 1:50 - 1:200; immunofluorescence: 1:50 - 1:200; immunoprecipitation (IP): 1:50 - 1:200; western blot: 1:500 - 1:2000
• color: colorless
• isotype: IgG
• immunogen sequence: PPKEWKPRQTYDDIDDVVIPAPIQQVVTGQSGLFTQYNIQKKAMTVGEYRRLANSEKYCTPRHQDFDDLERKYWKNLTFVSPIYGADISGSLYDDDVAQWN
• UniProt accession no.: O94953
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... KDM4B(23030)

Description

General description

Histone demethylase that specifically demethylates ′Lys-9′ of histone H3, thereby playing a role in histone code. Does not demethylate histone H3 ′Lys-4′, H3 ′Lys-27′, H3 ′Lys-36′ nor H4 ′Lys-20′. Only able to demethylate trimethylated H3 ′Lys-9′, with a weaker activity than KDM4A, KDM4C and KDM4D. Demethylation of Lys residue generates formaldehyde and succinate.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 50-150 of human KDM4B/JMJD2B (O94953).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

WB, IF/ICC, IP, ChIP

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1