SAB5702752
Anti-VAV3 Antibody, clone 9A10D8, Rabbit Monoclonal
Synonym(s):
vav 3 guanine nucleotide exchange factor
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About This Item
UNSPSC Code:
12352203
NACRES:
NA.46
biological source
rabbit
Quality Level
material
colorless
clone
9A10D8, monoclonal
form
liquid
mol wt
98 kDa
species reactivity
mouse, mouse
concentration
0.66 mg/mL
technique(s)
immunohistochemistry: 1:50 - 1:200
western blot: 1:500 - 1:2000
color
colorless
General description
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Immunogen
A synthetic peptide corresponding to a sequence within amino acids 700-800 of human VAV3 (Q9UKW4).
PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Application
WB, IHC
Storage Class
10 - Combustible liquids
wgk_germany
WGK 1
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