SAB5701992

Anti-BRMS1 Antibody, clone 5Y8J3, Rabbit Monoclonal

• Synonym(s): BRMS1, breast cancer metastasis-suppressor 1
• UNSPSC Code: 12352203
• NACRES: NA.46

Properties

• biological source: rabbit
• Quality Level: 100
• material: colorless
• clone: 5Y8J3, monoclonal
• form: liquid
• species reactivity: rat, human, rat
• concentration: 1.20 mg/mL
• technique(s): immunohistochemistry: 1:50 - 1:200
• color: colorless
• isotype: IgG
• immunogen sequence: MPVQPPSKDTEEMEAEGDSAAEMNGEEEESEEERSGSQTESEEESSEMDDEDYERRRSECVSEMLDLEKQFSELKEKLFRERLSQLRLRLEEVGAERAPE
• UniProt accession no.: Q9HCU9
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... BRMS1(25855)

Description

General description

This gene reduces the metastatic potential, but not the tumorogenicity, of human breast cancer and melanoma cell lines. The protein encoded by this gene localizes primarily to the nucleus and is a component of the mSin3a family of histone deacetylase complexes (HDAC). The protein contains two coiled-coil motifs and several imperfect leucine zipper motifs. Alternative splicing results in two transcript variants encoding different isoforms.

Immunogen

A synthetic peptide corresponding to a sequence within amino acids 1-100 of human BRMS1 (Q9HCU9).

PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.

Application

IHC

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 1