SAB4500776

Anti-EPHB1 antibody produced in rabbit

affinity isolated antibody

• Synonym(s): ELK, EPB1, EPHT2, EPTH2, Eph receptor B1
• MDL number: MFCD02096314
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: affinity isolated antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• mol wt: antigen 109 kDa
• species reactivity: human, mouse
• concentration: ~1 mg/mL
• technique(s): ELISA: 1:20000; immunofluorescence: 1:100-1:500; immunohistochemistry: 1:50-1:100
• NCBI accession no.: P54762
• UniProt accession no.: P54762
• shipped in: wet ice
• storage temp.: −20°C
• target post-translational modification: unmodified
• Gene Information: human ... EPHB1(2047)

Description

General description

Anti-EPHB1 Antibody detects endogenous levels of total EPHB1 protein.

EPHB1(ephrin type-B receptor 1) belongs to the Eph gene family of receptor tyrosine kinases. It is present in venous endothelial cells during embryonic development to adulthood. It is located on human chromosome 3q22.2.

Immunogen

The antiserum was produced against synthesized peptide derived from human EPHB1/2/3.

Immunogen Range: 631-680

Biochem/physiol Actions

EPHB1(ephrin type-B receptor 1) participates in carcinogenesis of RCC (renal cell carcinoma). It plays a major role in the growth of nervous and vascular system. It acts as a biomarker for squamous cell/adenosquamous carcinomas and adenocarcinomas of the gallbladder.

Features and Benefits

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Physical form

Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable