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Key Documents

SAB4301607

Sigma-Aldrich

Anti-CD63

affinity isolated antibody

Synonym(s):

LAMP-3, ME491, MLA1, OMA81H, TSPAN30

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50 μG
SGD 1,120.00

SGD 1,120.00

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50 μG
SGD 1,120.00

About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

SGD 1,120.00

Please contact Customer Service for Availability
New, lower price on this item!

biological source

rabbit

Quality Level

100

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous glycerol solution

species reactivity

human, mouse

technique(s)

immunohistochemistry: 1:25-1:100
western blot: 1:500-1:2000

accession no.

NP_001244318

UniProt accession no.

P08962

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antibody form

purified immunoglobulin

antibody form

purified immunoglobulin

antibody form

IgG fraction of antiserum

antibody form

affinity isolated antibody

biological source

mouse

biological source

mouse

biological source

rabbit

biological source

rabbit

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

species reactivity

human

species reactivity

human

species reactivity

human, rat, pig, horse, mouse, bovine, dog

species reactivity

human

technique(s)

western blot: 1 μg/mL

technique(s)

indirect ELISA: suitable, western blot: 1-5 μg/mL

technique(s)

immunohistochemistry: suitable, western blot: suitable

technique(s)

immunohistochemistry: 1:50- 1:200

General description

Cluster of differentiation (CD63) belongs to the tetraspanin family, with four transmembrane domains. It is localised in late endosomes and lysosomes. The gene is located on human chromosome 12q13.2. CD63 is a membrane bound glycoprotein.

Immunogen

Synthetic peptide of human CD63 molecule

Biochem/physiol Actions

Cluster of differentiation (CD63) acts as a platelet activation marker. It plays an important role in regulating cell proliferation, adhesion, motility and differentiation. CD63 acts as a prognostic marker for lung adenocarcinoma. Deficiency of CD63 is associated with Hermansky−Pudlak syndrome (HPS).

Features and Benefits

Evaluate our antibodies with complete peace of mind. If the antibody does not perform in your application, we will issue a full credit or replacement antibody. Learn more.

Physical form

Rabbit IgG in pH7.4 PBS, 0.05% NaN3, 40% Glycerol.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

  • Specification Sheet

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    Certificates of Analysis (COA)

    Lot/Batch Number
    80240192
    780240192
    761440192

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    Hermansky-Pudlak syndrome: a disease of protein trafficking and organelle function
    Wei ML
    Pigment Cell Research / Sponsored by the European Society for Pigment Cell Research and the International Pigment Cell Society, 19(1), 19-42 (2006)
    Trafficking and function of the tetraspanin CD63
    Pols MS and Klumperman J
    Experimental Cell Research, 315(9), 1584-1592 (2009)
    Dongdong Tian et al.
    International journal of molecular medicine, 50(1) (2022-05-28)
    Chronic obstructive pulmonary disease (COPD) is one of the major causes of death worldwide today, and its related morbidity has been predicted to show an increase in subsequent years. Recent studies have shown that Danshen, a Chinese herbal medicine, is
    Comprehensive whole genome array CGH profiling of mantle cell lymphoma model genomes
    De Leeuw RJ, et al.
    Human Molecular Genetics, 13(17), 1827-1837 (2004)
    Łukasz Zadka et al.
    The American journal of pathology, 191(12), 2147-2171 (2021-08-25)
    Three-dimensional (3D) imaging and quantitative analysis of extracellular vesicles (EVs) remain largely unexplored, mainly because of limitations in detection techniques. In this study, EVs from patients diagnosed with colorectal cancer (CRC) and ulcerative colitis were examined. To investigate the spatial
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