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Key Documents

SAB4300163

Sigma-Aldrich

Anti-phospho-RAC1 (pSer71) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-MGC111543 antibody produced in rabbit, Anti-MIG5 antibody produced in rabbit, Anti-TC-25 antibody produced in rabbit, Anti-p21-Rac1 antibody produced in rabbit, Anti-ras-related C3 botulinum toxin substrate 1 (rho family, small GTP binding protein Rac1) antibody produced in rabbit

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About This Item

MDL number:
MFCD01322704
UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

~28 kDa

species reactivity

rat, mouse, human

concentration

1 mg/mL

technique(s)

western blot: 1:500-1:1000

isotype

IgG

immunogen sequence

(P-L-SP-Y-P)

NCBI accession no.

NP_008839.2

UniProt accession no.

P63000

shipped in

wet ice

storage temp.

−20°C

target post-translational modification

phosphorylation (pSer71)

Gene Information

human ... RAC1(5879)

Related Categories

Immunogen

Peptide sequence around phosphorylation site of serine 71 (P-L-S(p)-Y-P), according to the protein RAC1.

Features and Benefits

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Target description

Rac1 encoded by this gene is a GTPase which belongs to the RAS superfamily of small GTP-binding proteins. Members of this superfamily appear to regulate a diverse array of cellular events, including the control of cell growth, cytoskeletal reorganization, and the activation of protein kinases. Two transcript variants encoding different isoforms have been found for this gene.

Physical form

Solution in phosphate-buffered saline containing 0.02% sodium azide and 50% glycerol

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
871511203

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Ramesh Rijal et al.
Molecular biology of the cell, 30(2), 242-255 (2018-11-22)
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X Zhao et al.
Osteoarthritis and cartilage, 28(5), 613-625 (2020-02-02)
Monocyte-derived macrophages, as the predominant immune cell type that is increased in inflamed synovium, play a vital role during knee osteoarthritis (KOA) progression. However, the mechanisms underlying the recruitment of circulating monocytes to osteoarthritic knees remain uncertain. Based on previous
Wei-Hong Zhao et al.
Leukemia research, 63, 28-33 (2017-11-03)
To determine the role and mechanism of EphB4 in dasatinib (DAS) resistance in advanced chronic myeloid leukemia (CML), we explored the EphB4-mediated apoptotic and matrix microenvironment pathway in human CML and K562 cell lines. Heparinized bone marrow samples were obtained

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