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Key Documents

SAB1410173

Sigma-Aldrich

Anti-EGLN3 antibody produced in rabbit

purified immunoglobulin, buffered aqueous solution

Synonym(s):

FLJ21620, HIFPH3, MGC125998, MGC125999, PHD3

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

purified immunoglobulin

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

antigen 27.3 kDa

species reactivity

human

technique(s)

western blot: 1 μg/mL

NCBI accession no.

NM_022073

UniProt accession no.

Q9H6Z9

shipped in

dry ice

storage temp.

−20°C

target post-translational modification

unmodified

Gene Information

human ... EGLN3(112399)

Immunogen

EGLN3 (NP_071356.1, 1 a.a. ~ 239 a.a) full-length human protein.

Sequence
MPLGHIMRLDLEKIALEYIVPCLHEVGFCYLDNFLGEVVGDCVLERVKQLHCTGALRDGQLAGPRAGVSKRHLRGDQITWIGGNEEGCEAISFLLSLIDRLVLYCGSRLGKYYVKERSKAMVACYPGNGTGYVRHVDNPNGDGRCITCIYYLNKNWDAKLHGGILRIFPEGKSFIADVEPIFDRLLFFWSDRRNPHEVQPSYATRYAMTVWYFDAEERAEAKKKFRNLTRKTESALTED

Physical form

Solution in phosphate buffered saline, pH 7.4

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
09047

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Lija Swain et al.
Journal of leukocyte biology, 96(3), 365-375 (2014-03-15)
On a molecular level, cells sense changes in oxygen availability through the PHDs, which regulate the protein stability of the α-subunit of the transcription factor HIF. Especially, PHD3 has been additionally associated with apoptotic cell death. We hypothesized that PHD3

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