SAB1309055

[KO Validated]Anti-YWHAG antibody produced in rabbit

[Knockout Validated],affinity isolated antibody, buffered aqueous solution

• Synonym(s): 14-3-3 protein gamma, Protein kinase C inhibitor protein 1, KCIP-1, 14-3-3 protein gamma, N-terminally processed, YWHAG
• UNSPSC Code: 12352203

Properties

• biological source: (Human)
• conjugate: unconjugated
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: polyclonal
• form: liquid
• mol wt: 28303Da
• species reactivity: mouse, human
• technique(s): flow cytometry: 1:10~50; immunohistochemistry (formalin-fixed, paraffin-embedded sections): 1:10~50; western blot: 1:500-1:2000
• isotype: IgG
• NCBI accession no.: P61982; P61983; P68252; Q5F3W6; Q6PC29; Q6PCG0; Q6NRY9
• storage temp.: -10 to -25°C
• target post-translational modification: unmodified
• Gene Information: human ... YWHAG(7532)

Description

General description

YWHAG belongs to the 14-3-3 family of proteins which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals, and this protein is 100% identical to the rat ortholog. It is induced by growth factors in human vascular smooth muscle cells, and is also highly expressed in skeletal and heart muscles, suggesting an important role for this protein in muscle tissue. It has been shown to interact with RAF1 and protein kinase C, proteins involved in various signal transduction pathways.

Specificity

This YWHAG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 63-92 amino acids from the N-terminal region of human YWHAG.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable