SAB1300724

Anti-Phospho-RASGRF1-S929 antibody produced in rabbit

IgG fraction of antiserum, buffered aqueous solution

• Synonym(s): Anti-Guanine nucleotide-releasing protein, Anti-Ras-GRF1, Anti-Ras-specific guanine nucleotide-releasing factor 1, Guanine nucleotide-releasing factor 1, Ras-specific nucleotide exchange factor CDC25
• UNSPSC Code: 12352203
• NACRES: NA.41

Properties

• biological source: rabbit
• conjugate: unconjugated
• antibody form: IgG fraction of antiserum
• antibody product type: primary antibodies
• clone: polyclonal
• form: buffered aqueous solution
• species reactivity: human
• technique(s): dot blot: suitable; indirect ELISA: 1:1000
• NCBI accession no.: NP_002882
• UniProt accession no.: Q13972
• shipped in: dry ice
• storage temp.: −20°C
• target post-translational modification: phosphorylation (pSer929)
• Gene Information: human ... RASGRF1(5923)

Description

General description

RASGRF1 is a guanine nucleotide exchange factor (GEF) similar to the Saccharomyces cerevisiae CDC25 gene product. Functional analysis has demonstrated that this protein stimulates the dissociation of GDP from RAS protein. Studies of the similar gene in mouse suggested that the Ras-GEF activity of this protein in brain can be activated by Ca2+ influx, muscarinic receptors, and G protein beta-gamma subunit. Mouse studies also indicated that the Ras-GEF signaling pathway mediated by this protein may be important for long-term memory.

Immunogen

RASGRF1 (NP_002882, )
This antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide corresponding to amino acid residues surrounding S929 of human RASGRF1.

Physical form

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide.

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: nwg
• flash_point_f: Not applicable
• flash_point_c: Not applicable