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Key Documents

PLA0156

Sigma-Aldrich

Rabbit anti-PPP5C Antibody, Affinity Purified

Powered by Bethyl Laboratories, Inc.

Synonym(s):

PP-T, PP5, PPP5, PPT, catalytic subunit, protein phosphatase 5, protein phosphatase T

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

antibody form

affinity purified immunoglobulin

antibody product type

primary antibodies

species reactivity

mouse, human

technique(s)

immunohistochemistry: 1:200-1:1,000
immunoprecipitation (IP): 2-5 μg/mg
western blot: 1:2,000- 1:10,000

accession no.

NP_006238.1

UniProt accession no.

shipped in

wet ice

storage temp.

2-8°C

Gene Information

rabbit ... PPP5C(5536)

Immunogen

The epitope recognized by PLA0156 maps to a region between residue 1 and 50 of human Protein Phosphatase 5, Catalytic Subunit using the numbering given in entry NP_006238.1 (GeneID 5536).

Physical form

Tris-buffered Saline containing 0.1% BSA containing 0.09% Sodium Azide

Other Notes

PPP5C is the protein phosphatase 5 catalytic unit that is a member of the large PPP family of serine/threonine protein phosphatases. PPP5C plays a role in mediating stress-activated signaling pathways and the DNA damage response. Unlike PP1, PP2A, and PPP4, which function as dimeric or trimeric enzymes, PPP5 functions as a monomer. PPP5 exists as a regulatory N-terminal tetratricopeptide repeat (TPR) domain fused to a C-terminal phosphatase catalytic domain. PPP5C has been demonstrated to associate with and regulate ATM and DNA-PK.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

12 - Non Combustible Liquids

wgk_germany

WGK 1

flash_point_f

Not applicable

flash_point_c

Not applicable


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