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Key Documents

EMU058491

MISSION^® esiRNA

Name: MISSION<SUP>®</SUP> esiRNA
Brand: SIGMA

targeting mouse Iqgap1

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About This Item

UNSPSC Code:

41105324

NACRES:

NA.51

description

Quality Level

100

product line

MISSION^®

form

lyophilized powder

esiRNA cDNA target sequence

AAACAGATCCCTGCCATCACCTGCATTCAGTCACAGTGGAGAGGATACAAACAGAAGAAGGCATATCAAGATCGGCTGGCTTACCTGCACTCCCATAAAGACGAAGTTGTGAAGATTCAGTCCCTTGCCAGGATGCATCAAGCTCGAAAGCGCTATAGAGATCGCCTACAGTATTTCCGAGACCATATAAATGACATTATCAAAATCCAGGCTTTCATTCGGGCCAACAAAGCTCGTGATGACTACAAGACTCTCATCAATGCTGAGGACCCGCCTATGATTGTGGTCCGAAAGTTTGTCCACCTCCTGGACCAAAGTGATCAGGACTTCCAGGAGGAACTTGATCTCATGAAGATGCGCGAGGAGGTCATCACCCTCATCCGTTCCAACCAGCAGCTGGAGAACGACCTCAACCTCATGGATATCAAAATCGGACTGCTGGTGAAGAACAAGATCACGCTGCAGGATGTGGTTTCCCATAGTAAAAAACTTACCAAAAAAAATAAGGAACAGCTGTCCGACATGATGATGATAAACAAGCAGAAGGGCG

Ensembl | mouse accession no.

ENSMUSG00000030536

NCBI accession no.

NM_016721

shipped in

ambient

storage temp.

−20°C

Gene Information

mouse ... IQGAP1(29875) , Iqgap1(29875)

Related Categories

MISSION® esiRNA

Oligos, qPCR Probes & Peptides

General description

MISSION^® esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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IQGAP1 Is Involved in Enhanced Aggressive Behavior of Epithelial Ovarian Cancer Stem Cell-Like Cells During Differentiation.

Lu Huang et al.

International journal of gynecological cancer : official journal of the International Gynecological Cancer Society, 25(4), 559-565 (2015-02-13)

Wide metastasis is one of characteristics of ovarian cancer. Cancer stem cells, as a source in cancer invasion and metastasis, possess powerful potential of differentiation. Scaffolding IQ domain GTPase-activating protein 1 (IQGAP1) plays a key role in the invasion and

Shigella Effector OspB Activates mTORC1 in a Manner That Depends on IQGAP1 and Promotes Cell Proliferation.

Richard Lu et al.

PLoS pathogens, 11(10), e1005200-e1005200 (2015-10-17)

The intracellular bacterial pathogen Shigella infects and spreads through the human intestinal epithelium. Effector proteins delivered by Shigella into cells promote infection by modulating diverse host functions. We demonstrate that the effector protein OspB interacts directly with the scaffolding protein

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