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EHU128201

Sigma-Aldrich

MISSION® esiRNA

targeting human DEPDC1

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About This Item

UNSPSC Code:
41105324
NACRES:
NA.51
Pricing and availability is not currently available.

description

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product line

MISSION®

form

lyophilized powder

esiRNA cDNA target sequence

GTTGCCATCGATGCTCTACAGTTATGTTGTTTGTTACTTCCCCCACCAAATCGTAGAAAGCTTCAACTTTTAATGCGTATGATTTCCCGAATGAGTCAAAATGTTGATATGCCCAAACTTCATGATGCAATGGGTACGAGGTCACTGATGATACATACCTTTTCTCGATGTGTGTTATGCTGTGCTGAAGAAGTGGATCTTGATGAGCTTCTTGCTGGA

Ensembl | human accession no.

ENSG00000024526

NCBI accession no.

NM_001114120

shipped in

ambient

storage temp.

−20°C

Gene Information

human ... DEPDC1(55635) , DEPDC1(55635)

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MISSION® esiRNA targeting human DEPDC1

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MISSION® esiRNA targeting human LRRC40

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MISSION® esiRNA

MISSION® esiRNA targeting human CHD7

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MISSION® esiRNA

esiRNA cDNA target sequence

GTTGCCATCGATGCTCTACAGTTATGTTGTTTGTTACTTCCCCCACCAAATCGTAGAAAGCTTCAACTTTTAATGCGTATGATTTCCCGAATGAGTCAAAATGTTGATATGCCCAAACTTCATGATGCAATGGGTACGAGGTCACTGATGATACATACCTTTTCTCGATGTGTGTTATGCTGTGCTGAAGAAGTGGATCTTGATGAGCTTCTTGCTGGA

esiRNA cDNA target sequence

CCCAAAGTGTTCCCTCACATCAAGCTTGGAGACATTGTAGAGATTGCACACCCCAACGATGAATACAGCCCTCTGCTTTTGCAGGTCAAGTCTCTTAAGGAAGATTTACAGAAGGAAACTATCAGTGTGGACCAGACTGTGACTCAAGTGTTCCGGCTGAGACCTTATCAGGATGTCTATGTTAATGTCGTAGACCCTAAGGATGTGACCCTTGACCTAGTGGAATTAACTTTTAAGGATCAGTATATTGGCCGTGGGGATATGTGGCGACTAAAGAAAAGTTTGGTCAGCACATGTGCCTATATCACCCAGAAGGTGGAGTTTGCTGGCATCAGAGCACAGGCTGGTGAACTGTGGGTTAAGAATGAGAAGGTCATGTGTGGCTACATCAGTGAAGATACCAGGGTGGTGTTTCGTTCTACGTCGGCTATGGT

esiRNA cDNA target sequence

GATGGTGGGAGCAGACAGATTTGACCAAACTAATAATATCAAACAATAAACTTCAGTCACTTACAGATGACCTGCGACTCTTGCCTGCACTGACTGTTCTTGATATACATGATAATCAGTTGACATCCCTTCCTTCTGCTATAAGAGAGCTAGAAAATCTTCAGAAACTTAATGTCAGCCATAATAAACTGAAAATACTCCCTGAAGAAATTACAAACCTAAGAAACCTGAAGTGCCTGTATCTCCAGCATAATGAATTAACCTGCATATCAGAGGGATTTGAACAACTTTCCAATTTAGAAGATTTAGATCTTTCAAACAATCATCTTACAACTGTTCCTGCTAGTTTTTCTTCTCTGTCCAGTCTGGTGCGACTCAATCTTTCTAGTAATGAACTGAAGAGTTTGCCAGCAGAA

esiRNA cDNA target sequence

TGTCCGCATGCTGTACTACCTAAGACAAGAAGTGATAGGAGACCAGGCGGATAAGATCTTAGAGGGTGCTGACTCAAGTGAAGCCGATGTGTGGATCCCTGAACCTTTCCATGCTGAAGTTCCTGCAGATTGGTGGGATAAGGAAGCAGACAAATCCCTCTTAATTGGAGTGTTCAAACATGGCTATGAGAAGTACAACTCCATGCGAGCTGACCCCGCGCTGTGCTTTCTGGAACGAGTCGGTATGCCTGATGCCAAGGCCATAGCTGCCGAGCAAAGAGGAACAGACATGCTAGCAGATGGTGGTGACGGGGGAGAATTTGATAGAGAAGATGAAGACCCAGAATATAAACCAACCAGAACACCGTTCAAAGATGAAATAGATGAATTTGCAAATTCTCCTTCAGAGGATAAGGAAGAATCCATGGAAATACATGCCACAGGTAAGCACA

Ensembl | human accession no.

ENSG00000024526

Ensembl | human accession no.

ENSG00000100150

Ensembl | human accession no.

ENSG00000066557

Ensembl | human accession no.

ENSG00000171316

Gene Information

human ... DEPDC1(55635), DEPDC1(55635)

Gene Information

human ... DEPDC5(9681), DEPDC5(9681)

Gene Information

human ... LRRC40(55631), LRRC40(55631)

Gene Information

human ... CHD7(55636), CHD7(55636)

NCBI accession no.

NM_001114120

NCBI accession no.

NM_001007188, NM_014662

NCBI accession no.

NM_017768

NCBI accession no.

-

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

form

lyophilized powder

General description

MISSION esiRNA are endoribonuclease prepared siRNA. They are a heterogeneous mixture of siRNA that all target the same mRNA sequence. These multiple silencing triggers lead to highly-specific and effective gene silencing.

For additional details as well as to view all available esiRNA options, please visit SigmaAldrich.com/esiRNA.

Legal Information

MISSION is a registered trademark of Merck KGaA, Darmstadt, Germany

Storage Class

10 - Combustible liquids

flash_point_f

Not applicable

flash_point_c

Not applicable

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    Anna Tosi et al.
    Oncoimmunology, 6(8), e1313371-e1313371 (2017-09-19)
    The identification of universal tumor-specific antigens shared between multiple patients and/or multiple tumors is of great importance to overcome the practical limitations of personalized cancer immunotherapy. Recent studies support the involvement of DEPDC1 in many aspects of cancer traits, such
    Alboukadel Kassambara et al.
    PloS one, 8(4), e62752-e62752 (2013-05-07)
    High throughput DNA microarray has made it possible to outline genes whose expression in malignant plasma cells is associated with short overall survival of patients with Multiple Myeloma (MM). A further step is to elucidate the mechanisms encoded by these
    Ryogo Kikuchi et al.
    Journal of neuro-oncology, 133(2), 297-307 (2017-05-31)
    DEP domain containing 1 (DEPDC1) is a novel oncoantigen expressed in cancer cells, which presents oncogenic activity and high immunogenicity. Although DEPDC1 has been predicted to be a useful antigen for the development of a cancer vaccine, its pathophysiological roles

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