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Key Documents

AV47561

Sigma-Aldrich

Anti-POU6F1 (AB2) antibody produced in rabbit

affinity isolated antibody

Synonym(s):

Anti-BRN5, Anti-MPOU, Anti-POU domain, class 6, transcription factor 1, Anti-TCFB1

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About This Item

UNSPSC Code:
12352203
NACRES:
NA.41

biological source

rabbit

Quality Level

100

conjugate

unconjugated

antibody form

affinity isolated antibody

antibody product type

primary antibodies

clone

polyclonal

form

buffered aqueous solution

mol wt

33 kDa

species reactivity

horse, rabbit, rat, bovine, human, guinea pig

concentration

0.5 mg - 1 mg/mL

technique(s)

western blot: suitable

NCBI accession no.

NP_002693

UniProt accession no.

Q14863

shipped in

wet ice

storage temp.

−20°C

Gene Information

human ... POU6F1(5463)

General description

POU1F1 belongs to the POU domain-containing family of transcription factors that regulate cell-fate decisions. POU1F1 mutations have been linked to pituitary hormone deficiency.
Rabbit Anti-POU1F1 antibody recognizes rat, canine, human, bovine, and mouse POU1F1.

Immunogen

Synthetic peptide directed towards the N terminal region of human POU6F1

Application

Rabbit Anti-POU6F1 antibody is suitable for western blot applications at a concentration of 1μg/ml.

Biochem/physiol Actions

The POU6F1 gene encodes a protein that is part of a family of transcription factors which exhibit distinct temporal and spatial patterns of expression.

Sequence

Synthetic peptide located within the following region: TPQLLLNAQGQVIATLASSPLPPPVAVRKPSTPESPAKSEVQPIQPTPTV

Physical form

Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

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Storage Class

10 - Combustible liquids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
QC17433

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Anthony L Cook et al.
Pigment cell & melanoma research, 21(6), 611-626 (2008-11-06)
Several parallels between stem cell biology and tumour behaviour have been discovered in recent times. Such commonality is apparent in the unlimited capacity for cell division together with the lack of a differentiated phenotype in embryonic and adult stem cells
James P G Turton et al.
The Journal of clinical endocrinology and metabolism, 90(8), 4762-4770 (2005-06-02)
Mutations within the gene encoding the pituitary-specific transcription factor POU1F1 are associated with combined pituitary hormone deficiency (CPHD). Most of the affected individuals manifest GH, prolactin, and TSH deficiency. We have now screened 129 individuals with CPHD and isolated GH

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