81709

L-Proline

≥99.5% (NT), suitable for cell culture, BioUltra

• Synonym(s): (S)-Pyrrolidine-2-carboxylic acid
• Empirical Formula (Hill Notation): C₅H₉NO₂
• CAS Number: 147-85-3
• Molecular Weight: 115.13
• Beilstein/REAXYS Number: 80810
• EC Number: 205-702-2
• MDL number: MFCD00064318
• UNSPSC Code: 12352209
• eCl@ss: 32160406
• PubChem Substance ID: 57652885
• NACRES: NA.26

Properties

• Product Name: L-Proline, BioUltra, ≥99.5% (NT)
• product line: BioUltra
• Quality Level: 200
• assay: ≥99.5% (NT)
• form: powder or crystals
• optical activity: [α]20/D −85.0±1.0°, c = 5% in H₂O
• technique(s): cell culture | mammalian: suitable
• impurities: insoluble matter, passes filter test; ≤0.3% foreign amino acids
• ign. residue: ≤0.1%
• loss: ≤0.1% loss on drying, 20 °C (HV)
• color: colorless to white
• pH: 6.0-7.0 (25 °C, 1 M in H₂O)
• mp: 228 °C (dec.) (lit.)
• solubility: H₂O: 1 M at 20 °C, clear, colorless
• anion traces: chloride (Cl^-): ≤100 mg/kg; sulfate (SO₄^2-): ≤100 mg/kg
• cation traces: Al: ≤5 mg/kg; As: ≤0.1 mg/kg; Ba: ≤5 mg/kg; Bi: ≤5 mg/kg; Ca: ≤10 mg/kg; Cd: ≤5 mg/kg; Co: ≤5 mg/kg; Cr: ≤5 mg/kg; Cu: ≤5 mg/kg; Fe: ≤5 mg/kg; K: ≤50 mg/kg; Li: ≤5 mg/kg; Mg: ≤5 mg/kg; Mn: ≤5 mg/kg; Mo: ≤5 mg/kg; NH₄⁺: ≤20 mg/kg; Na: ≤50 mg/kg; Ni: ≤5 mg/kg; Pb: ≤5 mg/kg; Sr: ≤5 mg/kg; Zn: ≤5 mg/kg
• λ: 1 M in H₂O
• UV absorption: λ: 260 nm A_max: 0.05; λ: 280 nm A_max: 0.05
• SMILES string: OC(=O)[C@@H]1CCCN1
• InChI: 1S/C5H9NO2/c7-5(8)4-2-1-3-6-4/h4,6H,1-3H2,(H,7,8)/t4-/m0/s1
• InChI key: ONIBWKKTOPOVIA-BYPYZUCNSA-N

Description

Application

• Synthesis and in silico inhibitory action studies of azo-anchored imidazo[4,5-b]indole scaffolds against the COVID-19 main protease (M(pro)).: This publication discusses the synthesis of novel compounds using L-Proline and their potential as inhibitors against COVID-19, contributing to the ongoing search for effective treatments (Geedkar et al., 2024).

Other Notes

Protects enzymes against heat inactivation; Growth requirement of various microorganisms

Safety Information

• Storage Class: 13 - Non Combustible Solids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable
• ppe: Eyeshields, Gloves, type N95 (US)