ABS53

Anti-FHOD1 Antibody

from rabbit

• Synonym(s): formin homology 2 domain containing 1, FHOS, FH1/FH2 domain-containing protein, FHOS1, Formin homology 2 domain-containing protein 1, Formin homolog overexpressed in spleen 1
• UNSPSC Code: 12352203
• eCl@ss: 32160702
• NACRES: NA.41

Properties

• biological source: rabbit
• Quality Level: 100
• antibody form: purified antibody
• antibody product type: primary antibodies
• clone: polyclonal
• species reactivity: human
• technique(s): western blot: suitable
• NCBI accession no.: NP_037373
• UniProt accession no.: Q9Y613
• shipped in: wet ice
• target post-translational modification: unmodified
• Gene Information: human ... FHOD1(29109)

Description

General description

Formin-homology-2-domain containing protein 1 (FHOD1) is a member of the forming homology (FH) family, a group of proteins that act to regulate several cellular processes such as; embryonic patterning, cell survival, cytoskeletal organization, gene transcription and migration. FH proteins are able to regulate these processes through their interaction with actin binding proteins and by serving to bridge Rho-family GTPases with Src tyrosine kinase and the pathway for Wnt Signaling. As a member of the FH family, FHOD1 contains several characteristic domains including; a GTPase Binding Domain (GBD, a coiled coil, FH1 and FH2 domains, and a Diaphanous-like autoregulatory domain (DAD). FHOD1 is a necessary component in F-actin structure assembly and its activity is dependant on the RHO-Rock. Expression of FHOD1 is ubiquitous, but is highest in the spleen.

Specificity

This antibody recognizes FHOD1 at the N-terminus.

Immunogen

Epitope: N-terminus

Linear peptide corresponding to human FHOD1 at the N-terminus.

Application

Anti-FHOD1 Antibody is an antibody against FHOD1 for use in WB.

Research Category
Signaling

Western Blot Analysis: 2 µg/mL of this antibody detected FHOD1 on 10 µg of HeLa cell lysate.

Quality

Evaluated by Western Blot in Huvec cell lysate.

Western Blot Analysis: 2 µg/mL of this antibody detected FHOD1 on 10 µg of Huvec cell lysate.

Target description

~ 130 kDa observed

Physical form

Format: Purified

Protein G Purified

Purified rabbit polyclonal in buffer containing 0.1 M Tris-Glycine (pH 7.4), 150 mM NaCl with 0.05% sodium azide.

Storage and Stability

Stable for 1 year at 2-8°C from date of receipt.

Analysis Note

Control
Huvec cell lysate

Other Notes

Concentration: Please refer to the Certificate of Analysis for the lot-specific concentration.

Disclaimer

Unless otherwise stated in our catalog or other company documentation accompanying the product(s), our products are intended for research use only and are not to be used for any other purpose, which includes but is not limited to, unauthorized commercial uses, in vitro diagnostic uses, ex vivo or in vivo therapeutic uses or any type of consumption or application to humans or animals.

Safety Information

• Storage Class: 12 - Non Combustible Liquids
• wgk_germany: WGK 1
• flash_point_f: Not applicable
• flash_point_c: Not applicable