940739

TissueFab^® PODS Growth Factor Loaded Bioink Kit

Vascularization, Vis/405nm

Properties

• description: applications: cell proliferation, cell culture, tissue engineering
• form: viscous liquid (or gel)
• composition: PODS Human IGF-1, 25µg ; PODS Human PDGF-BB, 25µg ; PODS Human VEGF-165, 25µg ; TissueFab^® bioink, (Gel)MA Vis/405 nm, low endotoxin
• impurities: Bioburden (Total Aerobic): <5 CFU/ml; Bioburden (fungal): < 5 CFU/mL; Endotoxin: <50 EU/ml
• color: colorless to pale yellow
• pH: 6.5-7.5
• compatibility: (extrusion-based 3D bioprinting)
• storage temp.: −20°C

Description

General description

Rethink your bioinks with TissueFab^®
About the material:
The TissueFab(R) PODS Growth Factor Loaded Bioink Kit, vascularization, Vis/405 nm contains:
* Low endotoxin conductive bioink containing visible light photoinitiator
* Human PDGF-BB PODS
* Human VEGF-165 PODS
* Human IGF-1 PODS
Printing and crosslinking parameters:
*Suitable for extrusion-based bioprinting
*Visible light crosslinking at 405 nm wavelength
TissueFab(R) PODS Growth Factor Loaded Bioink kit, vascularization, Vis/405nm is a ready-to-use, GelMA based bioink kit which is formulated for high cell viability, printing fidelity, and is designed for extrusion-based 3D bioprinting and subsequent crosslinking with exposure to 405nm visible light. TissueFab(R) PODS Growth Factor Loaded Bioink kit, vascularization, GelMA Vis/405nm can be used with most extrusion-based bioprinters, is biodegradable and cytocompatible.
Included growth facors, PDGF-BB, VEGF-165, and IGF-1 are known to play crucial roles in promoting vasculogenesis and angiogenesis. Their inclusion with PODS (R) delivery system allows their sustained release within bioprinted constructs and retainment of 70% bioactivity after 6 months. When mixed with the bioink component, the included PODS (R) growth factors can promote angiogenesis.
More information and a step by step protocol can be found under the "More Documents" section of this page.

Application

TissueFab(R) PODS Growth Factor Loaded Bioink kit, vascularization, Vis/405nm enables the precise fabrication of 3D cell models and tissue constructs for research in 3D cell biology, tissue engineering, in vitro tissue models, and regenerative medicine.

Features and Benefits

Key Features and Benefits:
Each TissueFab(R) bioink is developed and tested to meet strict criteria to best suit researchers′ needs. This includes:
• Printability and rheological properties
• Crosslinking
• Cell viability
• Biocompatibility
• Low bioburden
• Low endotoxin
This product contains 10 ml of bioink solution and growth factors PODS packaged separately to allow for optimization.

Legal Information

TISSUEFAB is a registered trademark of Merck KGaA, Darmstadt, Germany

Safety Information

• Storage Class: 10 - Combustible liquids
• wgk_germany: WGK 3