Skip to Content
MilliporeSigma
All Photos(2)

Key Documents

View All Documentation

911550

Sigma-Aldrich

Bis-MPA-RAFT dendrimer

trimethylol propane core, generation 1

Synonym(s):

CTA functionalized dendrimer, Multi-arm RAFT

Sign Into View Organizational & Contract Pricing
All Photos(2)

About This Item

Empirical Formula (Hill Notation):
C99H104N6O18S12
Molecular Weight:
2050.69
UNSPSC Code:
12162002
NACRES:
NA.23
Pricing and availability is not currently available.

form

solid

mol wt

generation 1

no. Surface Groups

6

color

orange to red

storage temp.

−20°C

Related Categories

Compare Similar Items

View Full Comparison

Show Differences

1 of 4

This Item
246999204889432121
Ytterbium(II) iodide powder, ≥99.9% trace metals basis

494372

Ytterbium(II) iodide

Ytterbium(III) oxide 99.9% trace metals basis

246999

Ytterbium(III) oxide

Ytterbium(III) oxide 99.99% trace metals basis

204889

Ytterbium(III) oxide

Ytterbium(III) fluoride anhydrous, powder, 99.98% trace metals basis

432121

Ytterbium(III) fluoride

assay

≥99.9% trace metals basis

assay

99.9% trace metals basis

assay

99.99% trace metals basis

assay

99.98% trace metals basis

Quality Level

100

Quality Level

100

Quality Level

100

Quality Level

100

impurities

≤1000.0 ppm Trace Rare Earth Analysis

impurities

-

impurities

-

impurities

≤250.0 ppm Trace Rare Earth Analysis

mp

~999 °C (lit.)

mp

-

mp

-

mp

-

reaction suitability

reagent type: catalyst
core: ytterbium

reaction suitability

reagent type: catalyst
core: ytterbium

reaction suitability

reagent type: catalyst
core: ytterbium

reaction suitability

reagent type: catalyst
core: ytterbium

General description

  • Polymer architecture: Dendrimer
  • Generation: 1
  • End Group Functionality: RAFT
  • No. Surface Groups: 6
  • Calculated Mol. Wt.: 2050.7 g/mol
  • bis-MPA = 2,2-Bis(hydroxymethyl)propionic acid

Application

Bis-MPA dendritic molecules are based on 2,2-bismethylolpropionicacid (bis-MPA) building blocks. The hydrolysable linkers presented in this type of polymers allow their degradation into byproducts that can be reabsorbed by the body or into excretable non-toxic small molecules. Therefore, this group of dendritic polymers is biocompatible and biodegradable, making them suitable for biomedical applications.
The corona of this product is functionalized with RAFT agents, which allow direct controlled polymerization from the dendrimer surface. It can be readily used to construct multi-arm polymer structure using suitable acrylic monomers.

Storage Class

11 - Combustible Solids

wgk_germany

WGK 3

flash_point_f

Not applicable

flash_point_c

Not applicable

    • Choose from one of the most recent versions:

    Certificates of Analysis (COA)

    Lot/Batch Number
    MKCL8252

    Don't see the Right Version?

    If you require a particular version, you can look up a specific certificate by the Lot or Batch number.

    Search for a COA

    Already Own This Product?

    Find documentation for the products that you have recently purchased in the Document Library.

    Visit the Document Library

    Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications
    Garcia-Gallego, S. et al.
    Progress in Polymer Science, 48, 85-110 (2015)
    Patrik Stenström et al.
    Molecules (Basel, Switzerland), 23(8) (2018-08-17)
    Herein, we present the first evaluation of cationic dendrimers based on 2,2-bis(methylol)propionic acid (bis-MPA) as nonviral vectors for transfection of short interfering RNA (siRNA) in cell cultures. The study encompassed dendrimers of generation one to four (G1⁻G4), modified to bear
    Chemistry of multifunctional polymers based on bis-MPA and their cutting-edge applications
    Progress in Polymer Science, 48, 85-110 (2015)
    Anna Carlmark et al.
    Chemical Society reviews, 42(13), 5858-5879 (2013-05-01)
    Dendritic polymers are highly branched, globular architectures with multiple representations of functional groups. These nanoscale organic frameworks continue to fascinate researchers worldwide and are today under intensive investigation in application-driven research. A large number of potential application areas have been

    Articles

    The Potential of Dendritic Polyester Scaffolds as Biocompatible Drug Delivery Agents

    Professor Michael Malkoch provides an overview of the unique properties of dendritic molecules and their application in biomedical fields. He highlights bis-MPA dendritic scaffolds as a promising biodegradable and biocompatible platform for drug delivery applications

    Our team of scientists has experience in all areas of research including Life Science, Material Science, Chemical Synthesis, Chromatography, Analytical and many others.

    Contact Technical Service