17457

Methyl α-bromoisobutyrate

≥99.0% (GC)

• Synonym(s): Methyl 2-bromo-2-methylpropionate
• Linear Formula: (CH₃)₂CBrCOOCH₃
• CAS Number: 23426-63-3
• Molecular Weight: 181.03
• Beilstein/REAXYS Number: 1209484
• EC Number: 245-657-6
• MDL number: MFCD00017854
• UNSPSC Code: 12352100
• PubChem Substance ID: 57647652
• NACRES: NA.22

Properties

• Quality Level: 100
• assay: ≥99.0% (GC)
• form: liquid
• density: 1.399 g/mL at 20 °C (lit.)
• functional group: bromo; ester
• SMILES string: COC(=O)C(C)(C)Br
• InChI: 1S/C5H9BrO2/c1-5(2,6)4(7)8-3/h1-3H3
• InChI key: PQUSVJVVRXWKDG-UHFFFAOYSA-N

Description

Application

Atom Transfer Radical Polymerization (ATRP) initiator that will generate a polymer with a methyl end group

Methyl α-bromoisobutyrate was used in Reformatsky reaction to prepare 1,4-disubstituted 3,3-dimethylazetidin-2-ones.

Safety Information

• pictograms: GHS02
• signalword: Warning
• hcodes: H226
• pcodes: P210 - P233 - P240 - P241 - P242 - P243
• Hazard Classifications: Flam. Liq. 3
• Storage Class: 3 - Flammable liquids
• wgk_germany: WGK 3
• flash_point_f: 120.2 °F - closed cup
• flash_point_c: 49 °C - closed cup
• ppe: Eyeshields, Faceshields, Gloves, type ABEK (EN14387) respirator filter