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SRP0347

Sigma-Aldrich

EphB4 active human

recombinant, expressed in baculovirus infected Sf9 cells

Synonym(s):

EPH receptor B4, HTK, MYK1, TYRO11

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About This Item

CAS Number:
UNSPSC Code:
12352200
NACRES:
NA.77

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

form

aqueous solution

mol wt

50 kDa

packaging

pkg of 10 μg

technique(s)

activity assay: suitable
inhibition assay: suitable

NCBI accession no.

UniProt accession no.

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... EPHB4(2050)

General description

Human EPHB4 ( GenBank Accession No. NM_004444), amino acids 563-987 with N-terminal His tag, MW=50 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Unit Definition

One unit is defined as the amount of enzyme that will transfer 1 nmol phosphate to tyrosine substrate per minute at pH 7.4 and 30° C.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable


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Thomas Bruhl et al.
Circulation research, 94(6), 743-751 (2004-02-07)
Homeobox genes (Hox) encode for transcription factors, which regulate cell proliferation and migration and play an important role in the development of the cardiovascular system during embryogenesis. In this study, we investigated the role of HoxA9 for endothelial cell migration
Yusuke Takahashi et al.
Anticancer research, 34(6), 2913-2918 (2014-06-13)
Signaling induced by binding of erythropoietin-producing hepatoma-amplified sequence (EPH) receptors to their cell-surface ephrin ligands is implicated in hematopoiesis and growth of various cancer cells. However, the roles of EPH-ephrin signaling in leukemia have not been elucidated. We investigated the

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