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Key Documents

SRP0346

Sigma-Aldrich

EphB2 active human

recombinant, expressed in baculovirus infected Sf9 cells, ≥80% (SDS-PAGE)

Synonym(s):

CAPB, DRT, EK5, EPH receptor B2, ERK

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About This Item

CAS Number:
1537224-07-9
UNSPSC Code:
12352200
NACRES:
NA.32

biological source

human

recombinant

expressed in baculovirus infected Sf9 cells

Assay

≥80% (SDS-PAGE)

form

aqueous solution

mol wt

52 kDa

packaging

pkg of 10 μg

storage condition

avoid repeated freeze/thaw cycles

concentration

0.5 mg/mL

technique(s)

activity assay: suitable
inhibition assay: suitable

NCBI accession no.

NM_004442

UniProt accession no.

P29323

shipped in

dry ice

storage temp.

−70°C

Gene Information

human ... EPHB2(2048)

General description

Human EPHB2 ( GenBank Accession No. NM_004442), amino acids 569-end with N-terminal His-tag, MW=52 kDa, expressed in a Baculovirus infected Sf9 cell expression system.

Application

Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.

Storage Class Code

10 - Combustible liquids

WGK

WGK 1

Flash Point(F)

Not applicable

Flash Point(C)

Not applicable

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Certificates of Analysis (COA)

Lot/Batch Number
4020001003

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Madhu Macrae et al.
Cancer cell, 8(2), 111-118 (2005-08-16)
The EphA2 receptor tyrosine kinase is frequently overexpressed in many cancers, including 40% of breast cancers. Here, we show that EphA2 is a direct transcriptional target of the Ras-Raf-MAPK pathway and that ligand-stimulated EphA2 attenuates the growth factor-induced activation of
Hongshi Xu et al.
American journal of physiology. Renal physiology, 288(4), F855-F866 (2004-11-25)
EphA2, a member of the large family of Eph receptor tyrosine kinases, is highly expressed in epithelial tissue and has been implicated in cell-cell and cell-matrix interactions, as well as cell growth and survival. Expression of EphA2 mRNA and protein

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