SML2724

CC2-49

≥98% (HPLC)

• Synonym(s): EN6 inactive control, EN6 negative control, N-(3-Acetamido-4-fluorophenyl)-1-(2-fluorophenyl)-1H-pyrazole-4-carboxamide, N-[3-(Acetylamino)-4-fluorophenyl]-1-(2-fluorophenyl)-1H-pyrazole-4-carboxamide
• Empirical Formula (Hill Notation): C₁₈H₁₄F₂N₄O₂
• CAS Number: 2305350-97-2
• Molecular Weight: 356.33
• UNSPSC Code: 12352200
• NACRES: NA.77

Properties

• Quality Level: 100
• Assay: ≥98% (HPLC)
• form: powder
• color: white to beige
• solubility: DMSO: 2 mg/mL, clear
• storage temp.: 2-8°C
• SMILES string: Fc1c(cccc1)[n]2ncc(c2)C(=O)Nc3cc(c(cc3)F)NC(=O)C
• InChI: 1S/C18H14F2N4O2/c1-11(25)22-16-8-13(6-7-14(16)19)23-18(26)12-9-21-24(10-12)17-5-3-2-4-15(17)20/h2-10H,1H3,(H,22,25)(H,23,26)
• InChI key: NXUJHBGKNXUNKK-UHFFFAOYSA-N

Description

Biochem/physiol Actions

CC2-49 is a cysteine non-reactive EN6 analog that lacks lysosomal vacuolar H(+)-ATPase (v-ATPase)-modifying activity, cellular mTORC1 inhibitory potency, nor autophagy-inducing efficacy. CC2-49 is the recommended negative (inactive) control for EN6.

Cysteine non-reactive analog of and the recommended negative (inactive) control for EN6.

Safety Information

• Storage Class Code: 11 - Combustible Solids
• WGK: WGK 3